Memory-Enhancing Effect of a Supercritical Carbon Dioxide Fluid Extract of the Needles of<i>Abies koreana</i>on Scopolamine-Induced Amnesia in Mice

Kim, Kanghyun; Bu, Youngmin; Jeong, Seung-Il; Lim, Jong-Pil; Kwon, Young-An; Seok, Dong; Kim, JinMo; Jeon, Sora; Eun, Jae-Soon; Jeon, Hoon

doi:10.1271/bbb.50608

Cited by 32 publications

(29 citation statements)

References 19 publications

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“…Among them, a-pinene was identified in high amount and it has been reported to present an AChE inhibitory effect [35]. Both major components of the essential oil, such as a-pinene and b-pinene, were tested for their potential neuroprotective effects [36,37].…”

Section: Discussionmentioning

confidence: 99%

Antiamnesic and Antioxidants Effects of Ferulago angulata Essential Oil Against Scopolamine-Induced Memory Impairment in Laboratory Rats

et al. 2015

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Ferulago angulata (Apiaceae) is a shrub indigenous to western Iran, Turkey and Iraq. In traditional medicine, F. angulata is recommended for treating digestive pains, hemorrhoids, snake bite, ulcers and as sedative. In the present study, the effects of inhaled F. angulata essential oil (1 and 3%, daily, for 21 days) on spatial memory performance were assessed in scopolamine-treated rats. Scopolamine-induced memory impairments were observed, as measured by the Y-maze and radial arm-maze tasks. Decreased activities of superoxide dismutase, glutathione peroxidase and catalase along with increase of acetylcholinesterase activity and decrease of total content of reduced glutathione were observed in the rat hippocampal homogenates of scopolamine-treated animals as compared with control. Production of protein carbonyl and malondialdehyde significantly increased in the rat hippocampal homogenates of scopolamine-treated animals as compared with control, as a consequence of impaired antioxidant enzymes activities. Additionally, in scopolamine-treated rats exposure to F. angulata essential oil significantly improved memory formation and decreased oxidative stress, suggesting memory-enhancing and antioxidant effects. Therefore, our results suggest that multiple exposures to F. angulata essential oil ameliorate scopolamine-induced spatial memory impairment by attenuation of the oxidative stress in the rat hippocampus.

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Section: Discussionmentioning

confidence: 99%

Antiamnesic and Antioxidants Effects of Ferulago angulata Essential Oil Against Scopolamine-Induced Memory Impairment in Laboratory Rats

et al. 2015

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“…Volatiles from alpine needle leaves were extracted by SFE. The major components extracted were elemol (48), terpinen-4-ol (49), sabinene (22, Figure 4), 10(15)-cadinen-4-ol (50), α-terpineol (51), α-pinene (52) and γ-terpinene (53) (Figure 11) [73]. Eucalyptus globulus is an evergreen tree, one of the most widely cultivated trees native to Australia.…”

Section: Supercritical Fluid Extraction Of Fragrancesmentioning

confidence: 99%

Supercritical Fluid Extraction of Plant Flavors and Fragrances

2013

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Supercritical fluid extraction (SFE) of plant material with solvents like CO 2 , propane, butane, or ethylene is a topic of growing interest. SFE allows the processing of plant material at low temperatures, hence limiting thermal degradation, and avoids the use of toxic solvents. Although today SFE is mainly used for decaffeination of coffee and tea as well as production of hop extracts on a large scale, there is also a growing interest in this extraction method for other industrial applications operating at different scales. In this review we update the literature data on SFE technology, with particular reference to flavors and fragrance, by comparing traditional extraction techniques of some industrial medicinal and aromatic crops with SFE. Moreover, we describe the biological activity of SFE extracts by describing their insecticidal, acaricidal, antimycotic, antimicrobial, cytotoxic and antioxidant properties. Finally, we discuss the process modelling, mass-transfer mechanisms, kinetics parameters and thermodynamic by giving an overview of SFE potential in the flavors and fragrances arena.

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“…Halla. Recent reports demonstrated that A. koreana has several medicinal functions, including antitumor [18,19] and memory-enhancing effects [20]. In addition, Jeong et al [21] elucidated 68 chemical components and demonstrated the anti-microbial activity of AKE.…”

Section: Resultsmentioning

confidence: 99%

Abies koreana Essential Oil Inhibits Drug‐Resistant Skin Pathogen Growth and LPS‐Induced Inflammatory Effects of Murine Macrophage

Yoon¹,

Kim²,

Oh³

et al. 2009

Lipids

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Since acne vulgaris is the combined result of a bacterial infection and the inflammatory response to that infection, we examined whether Abies koreana essential oil (AKE) possessed anti-inflammatory and antibacterial activities against skin pathogens. In this study, AKE showed excellent antibacterial activities against drug-susceptible and -resistant Propionibacterium acnes and Staphylococcus epidermidis, which are acne-causing bacteria. In addition, AKE reduced the LPS-induced secretion of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), IL-6, NO and PGE(2) in RAW 264.7 cells, indicating that it has anti-inflammatory effects. Therefore, we suggest that AKE may be an attractive candidate for promoting skin health.

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Memory-Enhancing Effect of a Supercritical Carbon Dioxide Fluid Extract of the Needles ofAbies koreanaon Scopolamine-Induced Amnesia in Mice

Cited by 32 publications

References 19 publications

Antiamnesic and Antioxidants Effects of Ferulago angulata Essential Oil Against Scopolamine-Induced Memory Impairment in Laboratory Rats

Antiamnesic and Antioxidants Effects of Ferulago angulata Essential Oil Against Scopolamine-Induced Memory Impairment in Laboratory Rats

Supercritical Fluid Extraction of Plant Flavors and Fragrances

Abies koreana Essential Oil Inhibits Drug‐Resistant Skin Pathogen Growth and LPS‐Induced Inflammatory Effects of Murine Macrophage

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