Memory Enhancing Effect of Ethanolic Extract of Stevia rebaudiana (Bert.)

Abstract

Suspension of ethanolic extract of leaves of Stevia rebaudiana bert. in gum acacia were administered orally to evaluate the memory enhancing activity in the aged rats. Memory enhancing effect was evaluated by using Morris water maze and elevated plus maze. Mean escape latency time (ELT) calculated each day during acquisition trial was used as an index of acquisition and mean time spent in target quadrant in search of missing platform provided an index of retrieval. Significant reduction in transfer latency (TL) value of retention indicated improvement of memory. Significant memory enhancing effect of ethanolic extract Stevia rebaudiana was observed in aged rats at 200 mg/kg p.o. dose.

Immunohistochemical evaluation of the influence of rebaudioside A on neurons containing acetylcholinesterase (AChE) in the rat’s hippocampus and striatum

“…U 2-letnich zwierząt, aktywność tego enzymu była znacząco niższa w porównaniu do grupy kontrolnej już po otrzymaniu najniższej dawki ekstraktu. Autorzy tłumaczą, że uzyskany efekt może być przypisany antyoksydacyjnym i przeciwzapalnym właściwościom stewii (14,15).…”

In-vitro Calcium Oxalate Crystallization Inhibition by Achyranthes aspera L. and Bryophyllum pinnatum Lam

“…Several phytochemicals like flavonoids, triterpenes, saponins, tannins, alkaloids, glycoside derivatives, proteins, tannins and steroids are reported to be responsible for antiurolithiatic effect by either inhibiting the formation of calcium oxalate crystals, preventing their attachment to renal cells or by their calcium channel blocking activity [14,[40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55].…”