Meniscus Regeneration Strategies

Abstract

Due to the important role of the meniscus concerning the integrity of the knee joint, meniscus tissue preserving techniques for the therapy of meniscal injuries seem to be reasonable. Due to a diminished self-healing capacity of meniscus particularly in the avascular zone, meniscus restoration is not always possible. Meniscus deficiency leads to functional restrictions and osteoarthritic changes in mid-and long term. Regenerative treatment augmentation for meniscal therapy and Tissue Engineering are promising approaches to preserve and restore as much meniscus tissue as possible. This chapter gives insights on current preclinical and clinical treatment strategies of meniscus and emphasizes on future perspectives like biological treatment augmentation for meniscal regeneration and Tissue Engineering of meniscus.