Meniscus Root Repair vs Meniscectomy or Nonoperative Management to Prevent Knee Osteoarthritis After Medial Meniscus Root Tears: Clinical and Economic Effectiveness

Faucett, Scott C.; Geisler, Benjamin P.; Chahla, Jorge; Krych, Aaron J.; Kurzweil, Peter; Garner, Abigail M.; Liu, Shan; LaPrade, Robert F.; Pietzsch, Jan B.

doi:10.1177/0363546518755754

Cited by 187 publications

(202 citation statements)

References 29 publications

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“…Another work compared an in-situ suture anchor repair and a transtibial technique with sutures tied over a titanium plate in a porcine model 10 In the transtibial pullout repair, the mean permanent displacement registered after 1000 cycles of a [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20] N load was 2.2 mm with the transtibial technique. Again, notorious methodological dissimilarities difficult contrast of the result with our study.…”

Section: Discussionmentioning

confidence: 99%

“…Biomechanical studies confirmed the importance of meniscal root integrity to preserve joint contact load distribution [1][2][3][4] and stability 5 . Meniscal root repair surgery aims to re-establish these meniscal functions 6,7 and to minimize progression of osteoarthritis 8 .…”

Section: Initial Biomechanical Properties Of Transtibial Meniscal Roomentioning

confidence: 99%

“…After preconditioning the specimen with 10 cycles of a load [1][2][3][4][5][6][7][8][9][10]N at 0.1 Hz 9,18 , it was loaded for 1000 cycles ]N at 0.5 Hz. This load range approximates tensile forces at the meniscal root under 500 N of joint compression in neutral rotation in a [0°-90°] range of flexion 11 .…”

Section: Biomechanical Testingmentioning

confidence: 99%

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Initial Biomechanical Properties of Transtibial Meniscal Root Repair are Improved By Using a Knotless Anchor as a Post-Insertion Tensioning Device

Prado-Nóvoa

Pérez-Blanca

Espejo-Reina

et al. 2020

Sci Rep

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The purpose of this study was to compare, in an in vitro porcine model, the initial biomechanical properties of transtibial root repairs using two different methods to fix the sutures: knotting them over a suture button (SB) or with a knotless anchor (KA) that allows post-insertion tensioning attached to the anterior tibial cortex. The study hypothesis was that the KA method provides lower displacements and higher resistance than the SB method.

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Section: Discussionmentioning

confidence: 99%

Section: Initial Biomechanical Properties Of Transtibial Meniscal Roomentioning

confidence: 99%

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Initial Biomechanical Properties of Transtibial Meniscal Root Repair are Improved By Using a Knotless Anchor as a Post-Insertion Tensioning Device

Prado-Nóvoa

Pérez-Blanca

Espejo-Reina

et al. 2020

Sci Rep

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“…3,4 Recently, an international consensus statement was made that emphasized the greater effectiveness of the meniscal root repair over meniscectomy and conservative treatments. 5,6 In my opinion, the study by Jiang, Everhart, Abouljoud, Kirven, Magnussen, Kae, and Flanigan 7 entitled "Biomechanical Properties of Posterior Meniscal Root Repairs: Systematic Review" provides excellent insight for clinicians to determine the appropriate surgical technique for MMPRTs. The authors systematically reviewed the literature for the biomechanical properties of several meniscal root repair techniques: the fixation method (transtibial pullout repair and suture anchor repair), the configuration and material of the suture used in transtibial pullout repair, and the location of fixation (anatomic vs nonanatomic).…”

Section: See Related Article On Page 2189mentioning

confidence: 99%

Editorial Commentary: Save the Meniscal Root, Why Not?

Kim

2019

Arthroscopy: The Journal of Arthroscopic & Related Surgery

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The repair of the meniscal root in medial meniscal posterior root tears is receiving increasing interest as more and more research highlights the positive effects of this procedure on the biomechanical restoration of the meniscus. As a testament to the findings of these studies, an international consensus statement recently acknowledged, with several supporting findings from both biomechanical and clinical studies, the effectiveness of meniscal root repairs. Various root repair techniques have been developed with the overarching goal of restoring the structure and function of the meniscus. Yet several challenges such as obtaining robust and long-term healing of degenerative tissue and minimizing meniscal extrusion remain to be overcome.

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“…For knee OA, a large number of neutrophils and oxidative stress metabolites are locally induced, which can enhance damage and degeneration of the meniscus [4]. The meniscus plays an irreplaceable role in lubricating joints and maintaining the bio-mechanical properties of the knee joints, and so chronic degeneration is also an important cause of knee OA [5,6,7].…”

Section: Introductionmentioning

confidence: 99%

Clinical Significance of Inflammatory Factors Within the Synovial Fluids in Patients With Knee Osteoarthritis for Predicting Meniscus Degeneration Progression

Wang

Jiang

et al. 2020

Preprint

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Background: This research aims to investigate the expressions and clinical significance of inflammatory factors in the synovial fluid of the meniscus degeneration with knee osteoarthritis (OA). Methods: A total of 100 patients with meniscus degeneration in knee OA were divided into into stage II and III groups based on MRI imaging. The expressions of inflammatory factors including interleukin-1β (IL-1β), IL-17, tumor necrosis factor-α (TNF-α) and tumor growth factor-β1 (TGF-β1) in the knee joint fluid were determined by means of an ELISA and chemiluminescence assay. International general Lysholm score and correlation between the levels of four cytokines were further analyzed.Results: Compared with stage II group, patients in stage III group had significantly increased levels of IL-1β in the synovial fluid along with increases in TNF-α (P <0.05) and higher levels of IL-17 (P <0.05). In addition, stage II group also showed a decrease in TGF-β1 (P<0.05). The levels of IL-1β, TNF-α and IL-17 were negatively correlated with Lysholm score whilst TGF-β1 was positively correlated with Lysholm score (P<0.05). The values of the area under the receiver operating characteristic (ROC) curves for the four cytokines in the diagnosis of meniscus degeneration in knee OA were 0.652, 0.604, 0.714 and 0.391 respectively. Conclusions: The high expression levels of IL-1β, TNF-α and IL-17, and the low expression levels of TGF-β1 in knee joint fluid are related to the severity of meniscus injury in patients with knee OA. These cytokines are associated with the pathological development of knee injury and ultimately lead to the decline of knee joint function.

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Meniscus Root Repair vs Meniscectomy or Nonoperative Management to Prevent Knee Osteoarthritis After Medial Meniscus Root Tears: Clinical and Economic Effectiveness

Cited by 187 publications

References 29 publications

Initial Biomechanical Properties of Transtibial Meniscal Root Repair are Improved By Using a Knotless Anchor as a Post-Insertion Tensioning Device

Initial Biomechanical Properties of Transtibial Meniscal Root Repair are Improved By Using a Knotless Anchor as a Post-Insertion Tensioning Device

Editorial Commentary: Save the Meniscal Root, Why Not?

Clinical Significance of Inflammatory Factors Within the Synovial Fluids in Patients With Knee Osteoarthritis for Predicting Meniscus Degeneration Progression

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