Mermaid syndrome

Abstract

ÖzetSirenomeli olarak da adlandinlan denizkizi (mermaid) sendromu oidukça nadir görülen dogumsal bir bozukiuktur. Bu sendromda bebege denizkizi görünümünü veren yapifik bacakiann yam sira, agir üreme-bo §altim, mide-bagirsak, kalp-damar ve merkezi sinir sistemi bozukiuklari bulunur. Bu yazida yapi §ik bacakiann yam sira göbek kordonunda tek arter, böbrek yokiugu, akciger hipoplazisi, özofagus atrezisi, ventriküier septai defekt, anai atrezi, bagirsak atrezisi saptanan ve dogumunun beçinci saatinde kaybedilen denizkizi sendromu olgusu sunuimuçtur. (Türi< Ped Ar § 2013; 48:65-7) Anahtar sözcükler: Denizkizi, kaudal disgenezi, sirenomeli Summary Sirenomelia, also known as the mermaid syndrome, is a very rare congenitai anomaly characterized by iower iimb fusion and severe urogenital, gastrointestinal, cardiovascuier, central nervous system maiformations. We report a case of sirenomelia who had a singie umblicai artery, renal agenesis, pulmoner hypoplasia, esophageai atresia, ventricular septai defect, anai atresia, intestinal atresia and who was iost at fifth hour of life. (Turi< Arcti Ped 2013; 48; 65-7)

Sirenomelia (mermaid syndrome): a case report

“…Several risk factors related with the sirenomelia malformation are maternal diabetes, retinoic acid, exposure to heavy metals and teratogens, genetic factors, monozygotic twins, male gender, and mother’s age <20 years or >40 years ( 1 , 3–12 , 18 ). There is a strong relationship between sirenomelia and maternal diabetes; the relative risk ratio is 1/200-250, and this ratio was found to be 22% among the fetuses with anomaly ( 8 , 10 , 11 , 16–18 ).…”