Mesenchymal Chondrosarcoma Treated With Total En Bloc Spondylectomy for 2 Consecutive Lumbar Vertebrae Resulted in Continuous Disease-Free Survival for More Than 5 Years

Matsuda, Yoshiro; Sakayama, Kenshi; Sugawara, Yoshifumu; Miyawaki, Joji; Kidani, Teruki; Miyazaki, Tatsuhiko; Tanji, Nozomu; Yamamoto, Haruyasu

doi:10.1097/01.brs.0000210297.02677.66

Cited by 29 publications

(37 citation statements)

References 24 publications

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“…However, the indication of TES for spinal metastasis still remained controversial [18,19]. Interestingly, there were more cases with metastasis underwent TES than that with primary tumors in literature [1,2,4,5,8,17,18,[20][21][22][23]. We believed that it was mainly because that primary spinal tumors were rare with less than 5 % of all primary musculoskeletal tumors.…”

Section: Discussionmentioning

confidence: 99%

Modified total en bloc spondylectomy for thoracolumbar spinal tumors via a single posterior approach

Huang

Chen

et al. 2012

Eur Spine J

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Purpose The objectives of this study were to describe our surgical management with a modified total en bloc spondylectomy (TES) and to evaluate the clinical effects in patients with thoracolumbar tumors. Methods Sixteen consecutive patients with thoracolumbar neoplasms underwent a modified TES via single posterior approach followed by dorsoventral reconstruction from December 2008 to July 2011. Details of the modified technique were described and the patients' clinical information was retrospectively reviewed and analyzed. Results Significant improvements in neurological function were achieved in most of the patients. Local pain or radicular leg pain was relieved postoperatively. The mean operation time was 7.2 h, with an average blood loss of 2,300 ml. No major complications, instrumentation failure or local recurrence was found at the final follow-up. Five patients died of the disease during mean 14-month (3.0-23) follow-up. Conclusions The modified TES with a single posterior approach is feasible, safe and effective for thoracolumbar spine tumors.

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Section: Discussionmentioning

confidence: 99%

Modified total en bloc spondylectomy for thoracolumbar spinal tumors via a single posterior approach

Huang

Chen

et al. 2012

Eur Spine J

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“…Plain radiographs demonstrate spinal chondrosarcoma as a well-defined mass with internal calcification [33]. In case that the mass projects into the lung fields, a well-defined opacity may be seen (Figures 1(a) and 1(b)).…”

Section: Radiologic Features and Imagingmentioning

confidence: 99%

Spinal Chondrosarcoma: A Review

Katonis

Alpantaki

Michail

et al. 2011

Sarcoma

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Chondrosarcoma is the third most common primary malignant bone tumor. Yet the spine represents the primary location in only 2% to 12% of these tumors. Almost all patients present with pain and a palpable mass. About 50% of patients present with neurologic symptoms. Chemotherapy and radiotherapy are generally unsuccessful while surgical resection is the treatment of choice. Early diagnosis and careful surgical staging are important to achieve adequate management. This paper provides an overview of the histopathological classification, clinical presentation, and diagnostic procedures regarding spinal chondrosarcoma. We highlight specific treatment modalities and discuss which is truly the most suitable approach for these tumors. Abstracts and original articles in English investigating these tumors were searched and analyzed with the use of the PubMed and Scopus databases with “chondrosarcoma and spine” as keywords.

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“…In the 1990s, Tomita (from our institute) developed and popularized the procedure known as "total en bloc spondylectomy" (TES), which is designed to achieve the complete oncological resection of spinal tumors 4,5) . This procedure has proven to provide excellent local control [6][7][8][9][10] , and is now widely accepted by spinal and musculoskeletal tumor surgeons [11][12][13][14][15][16][17][18][19][20][21] . TES has been used in selected patients with solitary spinal metastasis, and long-term follow-up has also been reported [22][23][24] .…”

Section: Introductionmentioning

confidence: 99%

Risk factors of instrumentation failure after multilevel total en bloc spondylectomy

Yoshioka

Murakami

Demura

et al. 2017

Spine Surg Relat Res

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Abstract:Introduction: Multilevel total en bloc spondylectomy (TES) is required to secure oncologically adequate resection margins. However, no useful information has been reported for spinal reconstruction after multilevel TES. Therefore, this study set out to assess the clinical and radiological outcomes of spinal reconstruction after multilevel TES. Methods: Forty-eight patients treated with multilevel TES at our institute were included in the analysis. Reconstruction was achieved with posterior pedicle screw fixation and an anterior titanium mesh cage filled with iliac autograft in all cases. Spinal shortening was performed to increase spinal stability from the reconstruction. Instrumentation failure and radiological findings were evaluated with radiography and computerized tomography (CT). Results: After excluding one patient whose general condition was deteriorating, radiological evaluations of 47 patients were performed over a period of more than a year. The follow-up time was 17 to 120 months (mean: 70.2 months). Instrumentation failure occurred in one patient (5.9%) after thoracic multilevel TES, in 4 patients (25.0%) after thoracolumbar multilevel TES, and in 3 patients (42.9%) after lumbar multilevel TES. No instrumentation failure was observed in cervicothoracic cases. Cage subsidence (>2 mm) occurred in 30 patients (63.8%). In 22 of them, subsidence appeared on the CT one month after surgery. The risk factors of instrumentation failure included a multilevel TES below the thoracolumbar level and a long span of vertebral resection. There was no instrumentation failure in any of the 11 "disc-to-disc cutting" cases. Conclusions: This study identified the risk factors of instrumentation failure after multilevel TES. There is a high risk of instrumentation failure in cases of long vertebral resection below the thoracolumbar level. On the other hand, our reconstruction method can be successful for multilevel TES above the thoracic level.

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Mesenchymal Chondrosarcoma Treated With Total En Bloc Spondylectomy for 2 Consecutive Lumbar Vertebrae Resulted in Continuous Disease-Free Survival for More Than 5 Years

Cited by 29 publications

References 24 publications

Modified total en bloc spondylectomy for thoracolumbar spinal tumors via a single posterior approach

Modified total en bloc spondylectomy for thoracolumbar spinal tumors via a single posterior approach

Spinal Chondrosarcoma: A Review

Risk factors of instrumentation failure after multilevel total en bloc spondylectomy

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