Mesenchymal Stem Cell Therapy For COVID-19; Is A New Challenge Review

Abstract

"Coronavirus" is the word that absolutely isn't forgotten by everybody who lives in the first half of the twenty-first century. COVID19, as a pandemic, has driven numerous researchers from various biomedical fields to discover arrangements or therapies to deal with the pandemic. Nonetheless, no standard treatment for this infection has been found to date. Presumably, preventing the acute severe respiratory infection type of COVID-19 as the most risky period of this disease can be useful for the therapy and decrease of the death rate. In such manner, mesenchymal stem cells (MSCs)-based immunomodulation treatment has been proposed as a reasonable restorative methodology and a several clinical studies have started. Recently, MSCs as indicated by their immunomodulatory and regenerative properties stand out in clinical trials. After the intravenous transplantation of MSCs, a large population of cells gathers in the lung, which they close by immunomodulatory impact could protect alveolar epithelial cells, recover the respiratory microenvironment, prevent pneumonic fibrosis, and cure lung dysfunction. Given the vulnerabilities here, we checked on detailed clinical preliminaries and theories to give helpful data to scientists and those keen on stem cell therapy.In this study, we considered this new way to deal with improve patient's immunological reactions to COVID-19 utilizing MSCs and talked about the parts of this proposed treatment. Nonetheless, right now, there are no affirmed MSC-based methodologies for the anticipation or potentially treatment of COVID-19 patients however clinical preliminaries progressing.

Neurosteroid, Natural And Anabolic Steroids: Physiological, Immunological And Histopathological Study on Hyperlipidaemic Albino Rats

“…Atherosclerosis develops as a result of the accumulation of lipids (mainly cholesterol) in the walls of the arteries, which contracts the blood vessels and impairs blood flow. Rates of morbidity and mortality increased in the presence of other common associated conditions as hypertension, diabetes mellitus, and renal disorders (Naser et al, 2021;Yao et al, 2020).…”