Mesenchymal Stem Cells and Extracellular Vesicles: An Emerging Alternative to Combat COVID-19

Abstract

The global SARS-CoV-2 outbreak has been accompanied with severe socio-economic and health burdens that will ripple through history. It is now known that SARS-CoV-2 induces a cytokine storm that leads to acute respiratory distress syndrome and systemic organ damage. With no definitive nor safe therapy for COVID-19 as well as the rise of viral variants the need for an urgent treatment modality is paramount. Mesenchymal stem cells (MSCs) and their extracellular vesicles (EVs) have long been praised for their anti-viral, anti-inflammatory and tissue regenerative capabilities. MSCs and their EVs are now being studied for their possible use as a treatment modality for COVID-19. In this review we explore their capabilities and outline the evidence of their use in ALI, ARDS and COVID-19.

Dental Anxiety Associated with Visiting Dental Clinics before and after Getting COVID-19 Vaccine

“…The novel Coronavirus disease, COVID-19, caused by Severe acute respiratory syndrome cornovirus-2 (SARS-CoV-2), rapidly progressed into the global pandemic since the first case was detected in Wuhan, China in December, 2019 [1][2][3][4][5]. As of February 25, 2022 there are about 431 million cases and over 5.93 million deaths worldwide [6].…”

Emergence of teledentistry during COVID-19 for management of dental services

“…The novel Coronavirus disease, COVID-19, caused by Severe acute respiratory syndrome cornovirus-2 (SARS-CoV-2), swiftly evolved into the worldwide epidemic ever since the first case was identified in Wuhan, China in December, 2019. [1][2][3][4][5] As of June 24, 2022 there are about 542 million cases and over 6.33 million deaths worldwide. 6 The most impacted countries include the United States of America, India and Brazil with about 86.7 million, 43.4 million and 32 million cases, and about 1.01 million, 0.52 million, 0.67 million deaths, respectively.…”