Mesenchymal stem cells can be obtained from the human saphena vein

Multilineage stem cells in the adult

“…14,15 Moreover, MSC could be derived from isolated blood vessels, reinforcing the possibility that these stem cells are of vascular affiliation. 16 …”

Stem/Progenitor Cells in Vascular Regeneration

“…48 Mesenchymal stem cells can be isolated from the internal surface of human saphenous vein and cultivated in vitro. 49 They form a semiconfluent layer of spindle-shaped cells that are CD13+, CD29+, CD44+, CD34−, CD45−, CD14−, CD54+, CD106−, CD90+, KDR−, cadherin-5−, HLA class I+, and HLA-DR−. Gene expression analysis revealed that the cells express mesenchymal stem cell markers and can differentiate in a similar pattern to bone marrow-derived mesenchymal stem cells.…”

“…Gene expression analysis revealed that the cells express mesenchymal stem cell markers and can differentiate in a similar pattern to bone marrow-derived mesenchymal stem cells. 49 Thus, these stem cells were found in both the vessel wall and the bone marrow.…”

Mesenchymal Stem Cells and Platelet Derived Concentrates in Regenerative Medicine

“…Mesenchymal stem cells are a significant type of adult stem cells that they can extracted from a variety of tissue ( Figure 1), including adipose tissue [1][2][3][4], skeletal muscle tissue [5], synovial membranes [6], cervical tissue [7], saphenous veins [8], periodontal ligaments [9], Wharton's jelly [10], umbilical cord blood [11], umbilical cords [12], amniotic fluid [13], dental pulp [14], placentae [15], lung tissue [16,17], liver tissue [18,19], and dermal tissue [19].…”