Mesenteric Panniculitis—First Case Series After Bariatric Surgery

Nasta, Amrit Manik; Patel, Dipti; Shrivastav, Om; Goel, Madhu; Shrimal, Anurag; Gupte, Amit; Goel, Ramen

doi:10.1007/s11695-017-3103-x

Cited by 4 publications

(1 citation statement)

References 10 publications

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“…Выделяются наиболее распространенные хирургические операции, приводящие к развитию склерозирующего мезентерита [40,41]. В последних сообщениях мезентериальный панникулит наблюдался у пациентов, перенесших бариатрическую операцию, а также неоднократно высказывалось предположение о ишемическом или воспалительном эффекте химиотерапии [42,43].…”

Section: этиология и патогенез заболеванияunclassified

Sclerosing mesenteritis as a surgical problem: a review of the literature and own clinical observation

Bogachev,

Boldin,

Golosnitskiy

et al. 2024

Ambulatornaya khirurgiya

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The problem of studying the pathology of mesenteric fat of the small intestine in surgical practice has not yet received enough attention. A number of questions remain unresolved regarding the etiology and pathogenesis of mesenteric diseases, their possible connection with benign and malignant diseases, methods of their laboratory and instrumental diagnosis, possible options for conservative and surgical treatment, as well as systematization and structuring of the classification. One of the poorly studied representatives of diseases of the mesentery of the small intestine continues to be Sclerosing mesenteritis, characterized by various histological variants of damage to mesenteric fat and a varied nonspecific clinical picture. Taken together, this leads to certain difficulties in diagnosis, patients seeking access to doctors of various profiles, which ultimately negatively affects the results of treatment and can lead to social maladjustment and possible disability. Reports on the occurrence of this pathology in the medical literature are few and, as a rule, describe extremely rare clinical cases. However, in recent years, the frequency of detection of this pathology continues to grow steadily, which is associated with the progressive aging of the population, a high degree of surgical activity in relation to urgent diseases of the abdominal organs, and the improvement of instrumental diagnostic methods. Issues of etiology, pathogenesis, differential diagnosis of this disease and its possible connection with the paraneoplastic process currently continue to cause debate. Further accumulation of clinical experience, a better understanding of the pathogenesis of the disease, and improvement of imaging techniques will allow us to develop clearer diagnostic and clinical criteria, narrow the diagnostic search and, ultimately, improve and standardize treatment. The article provides a review of the literature on this rare surgical pathology, presents our own clinical observation, and discusses diagnostic issues and treatment options for this disease.

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Section: этиология и патогенез заболеванияunclassified

Sclerosing mesenteritis as a surgical problem: a review of the literature and own clinical observation

Bogachev,

Boldin,

Golosnitskiy

et al. 2024

Ambulatornaya khirurgiya

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Mesenteric Panniculitis Can Be Diagnosed by Examination and Cured by Comprehensive Therapy

Zhao

Xie

2021

Gastroenterology Nursing

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Mesenteric panniculitis is a rare, slowly progressive, benign, and chronic fibrous inflammatory disease that affects the adipose tissue of the mesentery. In the present study, we aim to investigate its clinical presentations, computed tomography/sonography scan features, effectiveness of the treatment, and overall prognosis. We investigated various presentations, etiologies, diagnostic approaches, potential treatment modalities, and overall prognosis of mesenteric panniculitis. We present one case of mesenteric panniculitis with abdominal pain, which underwent steroid treatment regimens subsequently and gained weight moderately. An abdomen and pelvis cavity computed tomography scan showed misty mesentery, an ill-defined increase in the density of the peritoneal fat at the base of the mesentery with few small associated lymph nodes. The appearance is that of a panniculitis. His symptoms gradually decreased in intensity and disappeared totally within 1 month after oral prednisone 40 mg per day and moderate gain weight. Computed tomography scan features of the disease have recently been delineated clearly. Standard treatment strategy does not exist, and the current ways mainly consist of immunosuppressor or anti-inflammation agents. Overall prognosis is usually good and recurrence seems to be rare.

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A review of 17 cases of mesenteric panniculitis in Zhengzhou Ninth People’s Hospital in China

Wang,

Zhao,

Cao

et al. 2024

BMC Gastroenterol

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Purpose Mesenteric panniculitis (MP) represents the uncommon, benign and chronic inflammatory disorder affecting the mesenteric adipose tissues. Its etiology, diagnosis and treatment remain unnoticed. Our report focused on shedding more lights on this condition. Patients and methods Seventeen MP patients were identified by searching the electronic medical record system in the Zhengzhou Ninth People’s Hospital using the search terms “Mesenteric panniculitis” from October 2015 to March 2023. All cases were diagnosed with MP through computed tomography (CT). Their clinical features and treatments were analyzed. Results There were altogether 17 cases enrolled for this analysis. The male to female ratio was 8:9, and the median age at diagnosis was 64 (range: 37–96) years. There were 15 patients (88.2%) showing abdominal pain to varying degrees. The proportions of symptoms of nausea, vomiting and fever were 23.5%, 23.5% and 41.2%, respectively. Neoplastic disease was present in 3 patients (17.6%). Meanwhile, 9 patients (52.9%) had gallstones, 3 (17.6%) had cholecystitis and 1 (5.9%) had gallbladder polyps. Six patients (35.3%) received antibiotics treatment only and 1 (5.9%) received oral antibiotics and prednisone. One patient (5.9%) received antibiotics followed by prednisone treatment, because the symptoms were significantly relieved after antibiotic treatment, while the disease recurred soon after, and the symptoms improved again after prednisone treatment. The abdominal pain in 9 patients (52.9%) was relieved spontaneously. Two patients (11.8%) died, including one due to respiratory failure caused by pneumonia and the other one because of pancreatic cancer with lung and liver metastases. Conclusion MP is a poorly understood chronic inflammatory disease. Patients often have abdominal pain as the main symptom, accompanied by comorbidities in the gallbladder, and the prognosis is usually good after correct diagnosis and treatment, Therefore, the present report aims to promote the awareness among clinicians of patients with non-classic abdominal symptoms, so as to avoid misdiagnosis or missed diagnosis.

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Mesenteric Panniculitis—First Case Series After Bariatric Surgery

Cited by 4 publications

References 10 publications

Sclerosing mesenteritis as a surgical problem: a review of the literature and own clinical observation

Sclerosing mesenteritis as a surgical problem: a review of the literature and own clinical observation

Mesenteric Panniculitis Can Be Diagnosed by Examination and Cured by Comprehensive Therapy

A review of 17 cases of mesenteric panniculitis in Zhengzhou Ninth People’s Hospital in China

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