Mesotocin and vasotocin, two neurohypophysial hormones in the ostrich, Struthio camelus

Saayman, Hesta S.; Naudé, Ryno J.; Oelofsen, Willem; Isaacson, L. C.

doi:10.1111/j.1399-3011.1986.tb03271.x

Cited by 7 publications

(1 citation statement)

References 15 publications

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“…Recent genomic analyses make it clear that MT is a different name for the same orthologous gene in mammals, oxytocin (OT), which resulted from a local duplication from vasotocin (Theofanopoulou et al., 2021). While the MT peptide differs from the mammalian OT peptide by a change in the 8th amino acid from arginine to isolucine, we will refer to this peptide using the recently proposed universal gene nomenclature—oxytocin—to aid in translation of our findings across vertebrates and to mitigate ongoing confusion around the gene's evolutionary history and nomenclature (Saayman et al., 1986; Theofanopoulou et al., 2021).…”

Section: Introductionmentioning

confidence: 99%

The neural distribution of the avian homologue of oxytocin, mesotocin, in two songbird species, the zebra finch and the canary: A potential role in song perception and production

Haakenson

Balthazart

Madison

et al. 2022

J of Comparative Neurology

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The avian homologue of oxytocin (OT), formerly called mesotocin, influences social behaviors in songbirds and potentially song production. We sought to characterize the distribution of OT peptide in the brain of two songbird species: canaries (Serinus canaria) and zebra finches (Taeniopygia guttata). To visualize OT, we performed immunocytochemistry using an antibody previously shown to identify OT in avian species. In both canaries and zebra finches, dense OT‐ir perikarya were located in the paraventricular nucleus (PVN), preoptic area (POA), supraoptic nucleus (SON), and medial bed nucleus of the stria terminalis (BNSTm). We also observed morphologically distinct OT‐ir cells scattered throughout the mesopallium. OT‐ir fibers were observed in the PVN, ventral medial hypothalamus (VMH), periaqueductal gray (PAG), intercollicular nucleus (ICo), and ventral tegmental area (VTA). We also observed punctate OT‐ir fibers in the song control nucleus HVC. In both male and female canaries, OT‐ir fibers were present in the lateral septum (LS), but innervation was greater in males. We did not observe this sex difference in zebra finches. Much of the OT staining observed is consistent with general distributions within the vertebrate hypothalamus, indicating a possible conserved function. However, some extra‐hypothalamic distributions, such as perikarya in the mesopallium, may be specific to songbirds and play a role in song perception and production. The presence of OT‐ir fibers in HVC and song control nuclei projecting dopaminergic regions provides anatomical evidence in support of the idea that OT can influence singing behavior—either directly via HVC or indirectly via the PAG, VTA, or POA.

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Section: Introductionmentioning

confidence: 99%