Metabolic Syndrome Components Worsen Lower Urinary Tract Symptoms in Women with Type 2 Diabetes

Tai, Huai‐Ching; Chung, Shiu-Dong; Ho, Chen Hsun; Tai, Tong Yuan; Yang, Wei‐Shiung; Tseng, Chin‐Hsiao; Wu, Huey Peir; Hong, Yuling

doi:10.1210/jc.2009-1492

Cited by 77 publications

(59 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This finding is plausible for many reasons. One, the association of LUTS with metabolic factors, including HDL, has been well-documented previously (Parsons et al, 2006(Parsons et al, , 2007Tai et al, 2010). It has been postulated that metabolic factors are involved in the pathogenesis of LUTS via vascular impairment, and consequent bladder hypoxia would impact the function of the bladder (McVary, 2006).…”

Section: Discussionmentioning

confidence: 98%

Alcohol Is Longitudinally Associated with Lower Urinary Tract Symptoms Partially Via High‐Density Lipoprotein

Suh

Shin

Hwang

et al. 2014

Alcoholism Clin & Exp Res

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 98%

Alcohol Is Longitudinally Associated with Lower Urinary Tract Symptoms Partially Via High‐Density Lipoprotein

Suh

Shin

Hwang

et al. 2014

Alcoholism Clin & Exp Res

View full text Add to dashboard Cite

show abstract

“…Tai et al . [16] also suggested that MS may especially influence LUTS and OAB in diabetic women, probably by compounding the effect of peripheral neuropathy.…”

Section: Discussionmentioning

confidence: 99%

A study of bladder dysfunction in women with type 2 diabetes mellitus

Karoli

Bhat

Fatima

et al. 2014

Indian J Endocr Metab

View full text Add to dashboard Cite

Introduction:Diabetes mellitus has been associated with an earlier onset and increased severity of urologic diseases that often result in debilitating urologic complications. Diabetic bladder dysfunction refers to a group of bladder symptoms occurring in patients with diabetes mellitus ranging from bladder over activity to impaired bladder contractility.Aim:Bladder dysfunction is an under evaluated issue in women with diabetes. Aim of our study was to investigate prevalence of bladder dysfunction and its relation with other chronic complications of diabetes in women with type 2 diabetes.Materials and Methods:In a hospital-based cross sectional study, a cohort of women with type 2 diabetes mellitus who had lower urinary tract symptoms (LUTS) were enrolled. We used the American Urological Association Symptom Index (AUA-SI) to assess the severity of LUTS and the Indevus Urgency Severity Scale (IUSS) to assess presence of overactive bladder (OAB). Age-BMI- matched controls that did not have diabetes but had lower urinary tract symptoms were also studied and compared with women with type 2 diabetes. Urodynamic evaluation was done in willing patients.Results:LUTS attributable to bladder dysfunction were reported in 67% of women with type 2 diabetes after exclusion of other causes. Out of them, 36% had moderate to severe LUTS (total AUA-SI score >7). Prevalence of OAB was 53%. Urodynamic evaluation revealed presence of stress urinary incontinence in 48% patients and changes of detrusor over activity and detrusor under activity in 23% and 11% patients, respectively. Among the chronic complications of diabetes, peripheral neuropathy, nephropathy, and presence of metabolic syndrome were significantly associated with moderate to severe LUTS and OAB.Conclusion:Bladder dysfunction is a highly prevalent complication in women with diabetes. Chronic complications of diabetes especially neuropathy, nephropathy, and presence of metabolic syndrome are important predictors of bladder dysfunction.

show abstract

“…They also indicated that compared with the nonMetS group, the MetS group reported significantly higher storage and total symptom scores and a borderline increase in voiding symptom. When individual symptoms were compared, the average score of urgency, nocturia, and intermittency was significantly higher in the MetS group (11). In an other study, a total of 2371 men (mean age 46.1 years) and 731 women (mean age 53.9 years) were analyzed.…”

Section: Discussionmentioning

confidence: 93%

Assessment of Lower Urinary Tract Symptoms and Sexual Function in Women with Metabolic Syndrome

Borazan¹,

Temeltaş²,

Üçer³

et al. 2015

jus

View full text Add to dashboard Cite

Although there are a lot of studies to examine the association LUTS and sexual dysfunction with MetS in men, there are limited number studies to evaluate this association in women. We found that although the prevalence of LUTS and sexual dysfunction in women with MetS was higher than women without MetS, LUTS in these women with MetS did not significantly affect quality of life. ABSTRACTWhat's known on the subject? and What does the study add? ÖZET objectiveTo assess lower urinary tract symptoms and sexual function in premenopausal women with metabolic syndrome (MetS).

show abstract

Metabolic Syndrome Components Worsen Lower Urinary Tract Symptoms in Women with Type 2 Diabetes

Abstract: Our results suggest that MS may especially influence LUTS and OAB in diabetic women, probably by compounding the effect of peripheral neuropathy.

Cited by 77 publications

References 35 publications

Alcohol Is Longitudinally Associated with Lower Urinary Tract Symptoms Partially Via High‐Density Lipoprotein

Alcohol Is Longitudinally Associated with Lower Urinary Tract Symptoms Partially Via High‐Density Lipoprotein

A study of bladder dysfunction in women with type 2 diabetes mellitus

Assessment of Lower Urinary Tract Symptoms and Sexual Function in Women with Metabolic Syndrome

Contact Info

Product

Resources

About