Metabolism of chlorsulfuron by tolerant broadleaves

Hutchison, J.M.S.; Shapiro, Rebecca L.; Sweetser, Philip B.

doi:10.1016/0048-3575(84)90095-6

Cited by 62 publications

(38 citation statements)

References 5 publications

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“…were used: (a) biotype VLR1, which is susceptible to all herbicides registered for L. rigidum control in Australia at the manufacturer's recommended application rates, (b) biotype SLR31, which is resistant to diclofop-methyl and is cross-resistant to the wheat-selective sulfonylurea and imidazolinone herbicides chlorsulfuron, triasulfuron, metsulfuron-methyl, and imazamethabenz (4,5), and (c) biotype, WLR1, collected near Jerramungup in Western Australia (33057' S 118054'E) in a field that had been treated with chlorsulfuron during 7 consecutive years from 1983 to 1989, inclusive. The field had also been exposed to one or two applications of the nonselective herbicides N-(phosphonomethyl)glycine and 1,1'-dimethyl-4,4'-bipyridinium ion.…”

Section: Plant Materialsmentioning

confidence: 99%

Resistance to Acetolactate Synthase-Inhibiting Herbicides in Annual Ryegrass (Lolium rigidum) Involves at Least Two Mechanisms

Christopher

Powles²,

Holtum³

1992

Plant Physiol.

147

155

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WLR1, a biotype of Lolium rigidum Gaud. that had been treated with the sulfonylurea herbicide chlorsulfuron in 7 consecutive years, was found to be resistant to both the wheat-selective and the nonselective sulfonylurea and imidazolinone herbicides. Biotype SLR31, which became cross-resistant to chlorsulfuron following treatment with the aryloxyphenoxypropionate herbicide diclofop-methyl, was resistant to the wheat-selective, but not the nonselective, sulfonylurea and imidazolinone herbicides. The concentrations of herbicide required to reduce in vitro acetolactate synthase (ALs) activity 50% with respect to control assays minus herbicide for biotype WLR1 was greater than those for susceptible biotype VLR1 by a factor of >30, >30, 7, 4, and 2 for the herbicides chlorsulfuron, sulfometuron-methyl, imazapyr, imazathapyr, and imazamethabenz, respectively. ALS activity from biotype SLR31 responded in a similar manner to that of the susceptible biotype VLR1. The resistant biotypes metabolized chlorsulfuron more rapidly than the susceptible biotype. Metabolism of 50% of [phenyl-U-14C]chlorsulfuron in the culms of two-leaf seedlings required 3.7 h in biotype SLR31, 5.1 h in biotype WLR1, and 7.1 h in biotype VLR1. In all biotypes the metabolism of chlorsulfuron in the culms was more rapid than that in the leaf lamina. Resistance to ALS inhibitors in L. rigidum may involve at least two mechanisms, increased metabolism of the herbicide and/or a herbicide-insensitive ALS.

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Section: Plant Materialsmentioning

confidence: 99%

Resistance to Acetolactate Synthase-Inhibiting Herbicides in Annual Ryegrass (Lolium rigidum) Involves at Least Two Mechanisms

Christopher

Powles²,

Holtum³

1992

Plant Physiol.

147

155

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“…The sulfonylurea herbicide chlorsulfuron is hydroxylated to the phytotoxic 5-OH metabolite, which is immediately converted to glucose conjugates (Sweetser et al 1982), which do not inhibit ALS (Hutchison et al 1984). In our study, the introduction of CYP2C9 added a new route for the metabolization of imazosulfuron rice plants, which resulted in the enhancement of metabolization and herbicide tolerance in transgenic rice plants expressing human CYP2C9.…”

Section: Discussionmentioning

confidence: 85%

Enhanced expression of CYP2C9 and tolerance to sulfonylurea herbicides in transgenic rice plants

Hirose

Kawahigashi

Inoue

et al. 2005

Plant Biotechnology

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“…The rapid metabolism of chlorsulfuron in eastern black nightshade would appear to be responsible for the tolerance. The ability of flax (Linum usitatissimum) and black nightshade (Solanum nigrum) to metabolize chlorsulfuron was studied to determine if metabolism contributes to their tolerance to chlorsulfuron [54]. Shoot-treated plants metabolized more than 90% of parent herbicides.…”

Section: Metabolism Of Sulfonylurea Herbicides In Weedsmentioning

confidence: 99%

Herbicide Metabolism in Weeds — Selectivity and Herbicide Resistance

Jablonkai¹

2015

Herbicides, Physiology of Action, and Safety

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The metabolic detoxication/bioactivation pathways, the levels and activity of enzymes, and endogenous cofactors mediating these reactions in crops have been well documented; however, much less evidence has been accumulated in weed species. The herbicide metabolism as a selectivity factor is summarized with special attention to acetyl-CoA carboxylases (ACCase)-inhibiting aryloxyphenoxypropionate, protoporphyrinogen IX oxidase (PPO) inhibitor, carotenoid biosynthesis inhibitor clomazone, and acetolactate synthase (ALS) inhibitor imidazolinone and sulfonylurea herbicides in various weed species. The metabolism-based herbicide resistance related to these herbicide classes is also discussed along with the role and level of metabolizing enzymes and cofactors in weed species.

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Metabolism of chlorsulfuron by tolerant broadleaves

Cited by 62 publications

References 5 publications

Resistance to Acetolactate Synthase-Inhibiting Herbicides in Annual Ryegrass (Lolium rigidum) Involves at Least Two Mechanisms

Resistance to Acetolactate Synthase-Inhibiting Herbicides in Annual Ryegrass (Lolium rigidum) Involves at Least Two Mechanisms

Enhanced expression of CYP2C9 and tolerance to sulfonylurea herbicides in transgenic rice plants

Herbicide Metabolism in Weeds — Selectivity and Herbicide Resistance

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