Abstract:Early embryonic development arrest (EEDA) is a unique
form of early
spontaneous abortion in pregnant women, which is previously suggested
to be associated with metabolic abnormalities. Noninvasive biomarkers
would significantly improve its diagnosis and clinical outcome. Here,
we performed a targeted metabolomics study in plasma from EEDA patients
(n = 27) and normal pregnant women (NPW, n = 27) using liquid chromatography coupled with mass spectrometry
(LC–MS) to identify potential diagnostic marker metabolit… Show more
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