Metal Complexes with 8-Hydroxyquinoline: Synthesis and &amp;lt;i&amp;gt;In Vitro&amp;lt;/i&amp;gt; Antimicrobial Activity

Cipurković, Amira; Horozić, Emir; Marić, Snježana; Mekić, Lejla; Junuzović, Halid

doi:10.4236/ojapps.2021.111001

Cited by 18 publications

(9 citation statements)

References 19 publications

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“…The peak at 1567 cm 743 cm -1 [43]. The absorption band in capped HNTs spectra are similar to the uncapped ones; however, there is the appearance of a peak at 567 cm -1 , which is attributed to the metal(II)-nitrogen bond (Co-Inhibitor complex) [20]. The appearance of this peak is an indication of the formation of the metal-inhibitor complex on HNTs.…”

Section: Ftir Analysismentioning

confidence: 82%

“…5a, we can see two primary UV spectra at pH 2. The spectra for uncapped HNTs represent two main absorption peaks at 234 and 308 nm, demonstrating p-p* and n-p* transition in the quinoline ring [20]. The absorption spectra of capped HNTs represent three main absorption peaks at 237, 310, and 370 nm.…”

Section: Uv-vis Spectroscopic Analysis For Release Studiesmentioning

confidence: 95%

“…The absorption spectra of capped HNTs represent three main absorption peaks at 237, 310, and 370 nm. The peaks at 237 and 308 nm are due to the p-p* and n-p* transitions in 8HQ, which shifted slightly to a higher wavelength (batochrome shift) [20]. The peak at 370 nm can be associated with Co (II)-inhibitor charge transfer transitions [52,53].…”

Section: Uv-vis Spectroscopic Analysis For Release Studiesmentioning

confidence: 96%

“…HNTs can store inhibitors, whereas end stoppers are used to control the release of inhibitors [17][18][19]. Since HNTs are biocompatible and non-toxic, they are also used in biotechnological applications such as controlled drug release and tissue engineering [20,21].…”

Section: Graphical Abstract Introductionmentioning

confidence: 99%

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Polymeric smart coatings containing modified capped halloysite nanotubes for corrosion protection of carbon steel

et al. 2023

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A newly designed smart self-healing epoxy coating system comprised of modified halloysite nanotubes (HNTs) having capping is proposed for corrosion protection of steel. In the first step, HNTs were loaded with 8-hydroxyquinoline (8HQ), used as a corrosion inhibitor. Then the HNTs were sealed/capped using cobalt (II), aiming for an efficient and controlled release of the loaded inhibitor. The smart coatings were developed by reinforcing loaded HNTs into the epoxy matrix. The structural, thermal, mechanical, and electrochemical properties of capped modified HNTs and smart coatings were studied using various techniques. UV–Vis analysis depicted that the capping of the metal-inhibitor complex was decomposed at acidic pH resulting in a controlled release of the loaded inhibitor into HNTs. Electrochemical impedance spectroscopic (EIS) analysis of blank and smart coatings demonstrated that the low-frequency impedance modulus of smart coatings is 109 Ω.cm2 for 20 days compared to blank coatings (105 Ω.cm2), reflecting their excellent corrosion inhibition performance. The superior corrosion protection properties of these smart coatings can be ascribed to the controlled and efficient release of the loaded inhibitor from the capped HNTs. Finally, X-ray photoelectron spectroscopy (XPS) analysis of the steel substrate after the corrosion analysis revealed the adsorption of 8HQ on the steel surface, confirming the formation of iron complex due to the release of loaded inhibitor. This work demonstrated the adeptness of 8HQ in mitigating the corrosion due to the controlled and effective release of the inhibitor from capped HNTs because of dissociation of the metal-inhibitor complex (Co-8HQ).Kindly check and confirm the authors names are correctly identified.Checked Graphical abstract

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Section: Ftir Analysismentioning

confidence: 82%

Section: Uv-vis Spectroscopic Analysis For Release Studiesmentioning

confidence: 95%

Section: Uv-vis Spectroscopic Analysis For Release Studiesmentioning

confidence: 96%

Section: Graphical Abstract Introductionmentioning

confidence: 99%

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Polymeric smart coatings containing modified capped halloysite nanotubes for corrosion protection of carbon steel

et al. 2023

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“…Significant Tf binding of In(III) in blood serum is likely, while GaQ 3 interacts less with this protein. The complex band was shifted only in serum samples; the presence of HQ – Fe(II)/(III) or Cu(II) complexes can be excluded on the basis of the obtained spectra [ 49 , 50 ]. Formation of HQ – Mg(II) complex is not feasible even at physiological Mg(II) ion levels (0.7–1.0 mM) based on the available stability constants [ 51 ].…”

Section: Resultsmentioning

confidence: 99%

Solution speciation and human serum protein binding of indium(III) complexes of 8-hydroxyquinoline, deferiprone and maltol

2022

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Solution speciation and serum protein binding of selected In(III) complexes bearing O,O and O,N donor sets were studied to provide comparative data for In(III) and analogous Ga(III) complexes. Aqueous stability of the In(III) complexes of maltol, deferiprone, 8-hydroxyquinoline (HQ) and 8-hydroxyquinoline-5-sulfonate (HQS) was characterized by a combined pH-potentiometric and UV–visible spectrophotometric approach. Formation of mono, bis and tris-ligand complexes was observed. The tris-ligand complexes of HQ (InQ3) and deferiprone (InD3) are present in solution in ca. 90% at 10 µM concentration at pH = 7.4, while the tris-maltolato complex (InM3) displays insufficient stability under these conditions. Binding towards human serum albumin (HSA) and (apo)transferrin ((apo)Tf) of InQ3, InD3 and InM3 complexes and Ga(III) analogue of InQ3 (GaQ3) together with InCl3 was investigated by a panel of methods: steady-state and time-resolved spectrofluorometry, UV–visible spectrophotometry and membrane ultrafiltration. Moderate binding of InQ3 to HSA was found (log K′ = 5.0–5.1). InD3 binds to HSA to a much lower extent in comparison to InQ3. ApoTf is able to displace HQ, deferiprone and maltol effectively from their In(III) complexes. Protein binding of non-dissociated InQ3 was also observed at high complex-to-apoTf ratios. Studies conducted with the InQ3/GaQ3 – HSA – Tf ternary systems revealed the more pronounced Tf binding of In(III) via ligand release, while the original GaQ3 scaffold is preferably retained upon protein interactions and significant albumin binding occurs. Significant dissociation of InQ3 was detected in human blood serum as well. Graphical abstract

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“Smart” Sorbents Based on Iminodiacetic Acid for Selective Sorption of Heavy Metal Ions

Pylypenko,

Zaitseva,

Panayotova

2023

Lecture Notes in Networks and Systems

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Metal Complexes with 8-Hydroxyquinoline: Synthesis and <i>In Vitro</i> Antimicrobial Activity

Cited by 18 publications

References 19 publications

Polymeric smart coatings containing modified capped halloysite nanotubes for corrosion protection of carbon steel

Polymeric smart coatings containing modified capped halloysite nanotubes for corrosion protection of carbon steel

Solution speciation and human serum protein binding of indium(III) complexes of 8-hydroxyquinoline, deferiprone and maltol

“Smart” Sorbents Based on Iminodiacetic Acid for Selective Sorption of Heavy Metal Ions

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