Metal complexes with valuable biomolecules produced by Pseudomonas aeruginosa: a review of the coordination properties of pyocyanin, pyochelin and pyoverdines

Abstract

Pseudomonas aeruginosa is an opportunistic, Gram-negative bacterium, involved in severe infections associated with cystic fibrosis, pneumonia, burn wounds, ocular diseases, and immunosuppressive illnesses, and is a major cause of intrahospital...

A Practical Toolkit for the Detection, Isolation, Quantification, and Characterization of Siderophores and Metallophores in Microorganisms

“…NMR has also been used to study the ability of siderophores to form complexes with different metal ions. In a recent review, attention was devoted to the three natural products derived from Pseudomonas aeruginosa, namely, pyocyanin, pyochelin, and pyoverdine(s), and their ability to form complexes with Fe 2+ , Fe 3+ , Mn 2+ , Mn 3+ , Ga 3+ , Cr 3+ , Ni 2+ , Cu 2+ , Zn 2+ , and Cd 2+ , highlighting the use of NMR for the characterization of the pyochelin–Zn 2+ and −Ga 3+ complexes . Other examples include the characterization of the metal complexes of the siderophore desferriferricrocin with Fe 3+ , Cr 3+ , Al 3+ , Ga 3+ , Cu 2+ , and Zn 2+ ; while the authors were able to obtain the NMR spectra for Al 3+ , Ga 3+ , and Zn 2+ , spectra could not be obtained for Cu 2+ , Fe 3+ , and Cr 3+ due to line broadening from the paramagnetic nature of divalent copper and trivalent iron and chromium …”