Metal Toxicity in Humans Associated with Their Occupational Exposures Due to Mining

Burnase, Nishant; Jaiswal, Shraddha; Barapatre, Anand

doi:10.1007/978-3-030-99495-2_7

Cited by 7 publications

(4 citation statements)

References 177 publications

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“…Exposure to or inhalation of Cr may increase the risk of lung, nose and sinus cancer. Severe dermatitis and generally painless skin ulcers can be caused by exposure to Cr compounds (Burnase et al, 2022). The iron (Fe) content obtained in this study was higher than the WHO recommended limit of 0.1 mg/L.…”

Section: Discussioncontrasting

confidence: 53%

Mycological, Aflatoxin and Heavy Metals Composition of Dried Fish from Idi-ape Markets in Ilorin, Nigeria

Ajimati,

Awe,

Bale

2023

UJMR

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Fish is a cherished and highly sort after food that is widely eaten among many communities in Nigeria and the world at large, with good nutritional values. This study is aimed at evaluating the mycological flora, aflatoxin, proximate composition and heavy metals content in different dried fish samples. A total of three samples were used in this study which are; Salvetinus fortinacis, Heterotis niloticus and Malapterurus electricus. Aflatoxin detection in samples were carried out using High Performance Liquid Chromatography. The proximate analysis was carried out to determine the percentage nutritional value in each of the samples. Heavy metals detection was carried out using Atomic Absorption Spectrometer Buck scientific model 230. The result of the mycological evaluation revealed that the mean fungal count of all samples ranged from 1.5 ± 0.71 to 22.5 ± 4.95 (x102 CFU/g). With H. niloticus having the highest while M. electricus had the least. The proximate analysis results revealed percentage moisture of samples ranged from 4.382 ± 0.02 to 6.869± 0.009 (%) with H. niloticus having the highest and S. fortinacis having least value. Ash ranged from 3.518 ±0.18 to 4.424 ± 0.06 (%) with H. niloticus having the highest and S. fortinacis having the least. Percentage carbohydrate ranged from 14.179 ± 0.26 to 15.728 ± 0.33 (%) with H. niloticuss having the highest and S. fortinacis having the least. Calorific value ranged 1270.115 ± 1.12 to 1407.66 ± 1.87 (KJ/100g) with H. niloticus having the highest and S. fortinacis having the lowest. Percentage lipid ranged from 10.549 ± 0.08 to 14.293 ± 0.10(%) with H. niloticus having the highest and S. fortinacis having the least. Percentage Crude fibre ranged from 22.389 ± 0.19 to 29.310± 0.03 (%) with S. fortinacis having the highest and H. niloticus having the least. Percentage Protein ranged from 35.529 ± 0.00 to 38.062 ± 0.00(%) with S. fortinacis having the highest and M. electricus having the least. The presence of mycotoxin producing fungi in the different dried fish samples led to the presence of different Aflatoxins (known carcinogenic toxin) in the samples which is of a threat to human health.

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Section: Discussioncontrasting

confidence: 53%

Mycological, Aflatoxin and Heavy Metals Composition of Dried Fish from Idi-ape Markets in Ilorin, Nigeria

Ajimati,

Awe,

Bale

2023

UJMR

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“…Thereafter, deregulated inflammation can enhance the production of reactive oxygen species, which can aggravate liver injury [68]. Excessive intake of heavy metals in the body can cause headache, dizziness, insomnia, etc., whereas the severe ones can lead to serious damage to organs such as brain, kidney, and skin [69]. The various strategies adopted to reduce the harmful effects of heavy metals by L. plantarum in vivo include promoting the excretion of heavy metals and reducing the content of heavy metals in the tissues (Figure 4).…”

Section: Promoting Heavy Metal Excretionmentioning

confidence: 99%

Mechanisms of Health Improvement by Lactiplantibacillus plantarum Based on Animal and Human Trials: A Review

Hao,

Li,

Wang

et al. 2024

Fermentation

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Lactiplantibacillus plantarum is a candidate probiotic that has been included in the list of recommended biological agents for certification by the European Food Safety Authority. It has been found to be widely present in acidic-gruel, yogurt, cheese, kefir, kimchi, and so on. In this article, we have reviewed both preclinical and human studies related to the health promoting effects of L. plantarum that have been published for the past decade. We found that L. plantarum could significantly improve intestinal function, oral as well as skin health, promote neuro as well as immune regulation, and be effective against metabolic diseases, etc. L. plantarum primarily enters the body through the oral cavity and acts on the gastrointestinal tract to effectively improve the intestinal flora. It can affect the female reproductive endocrine system through interaction with estrogen, androgen, insulin, and other hormones, as well as improve the body’s allergic reaction and immunity by regulating Th1/Th2 response. Several prior reports also suggest that this Gram-positive bacterium can promote production and secretion of key neurotransmitters and neural activators in the intestinal tract by regulating the intestinal flora by directly or indirectly affecting the gut–brain axis through modulation of vagus nerve, cytokines, and microbial metabolites, thus relieving stress and anxiety symptoms in adults. This review is the first report describing the health promoting effects of L. plantarum, with the aim of providing a theoretical basis for the development of various beneficial applications of L. plantarum.

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“…The transformation of PTEs in soils from solid states to more bioavailable ionic or organometallic forms pose risks to plants, soil biota and human health (Sodhi et al, 2022). Human exposure to higher concentration of PTEs can result in severe health effects including cancers, organ damage, and developmental problems (Kormoker et al, 2021;Burnase et al, 2022). Qin et al (2021) estimated that the contaminated crop consumption in China leads to over 12,000 premature deaths and hundreds of thousands of cases of neurological issues and cardiovascular diseases each year.…”

Section: Introductionmentioning

confidence: 99%

Spatio-temporal evolution, exposure and health risk assessment of potentially toxic elements in China’s farmland soils

Aslam,

Bai,

et al. 2024

Preprint

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Widespread contamination of Chinese farmland soils by potentially toxic elements (PTEs) may pose emerging threats to food safety and human health. However, comprehensive nationwide investigations of pollution levels, trends and health risks are lacking. In this study, data from major agricultural regions across 10 Chinese provinces from 2007 to 2021 was analyzed to assess the concentrations of 8 key PTEs (arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu), mercury (Hg), lead (Pb), nickel (Ni), and zinc (Zn)) and determine spatial patterns, temporal accumulation, and current and future human health risks. The results showed that the average concentrations of Cd, Hg, Pb, Cu, Zn, Ni, Cr and As were 2.69, 2.47, 1.49, 1.14, 1.01 0.93, 0.89, and 0.89 times greater than their corresponding background values in China. Spatio-temporal analysis revealed increasing As pollution over time across provinces, with some areas reaching moderate-high pollution status. The geo-accumulation and pollution indices identified Cd, Hg, and Pb as the most heavily contaminated elements, with ingestion being the major exposure pathway increasing non-cancer and carcinogenic hazards. The study provided a baseline inventory of PTEs accumulation in Chinese farmland soils and evidence of potential health risks to guide priority areas for pollution control and soil remediation nationwide.

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Metal Toxicity in Humans Associated with Their Occupational Exposures Due to Mining

Cited by 7 publications

References 177 publications

Mycological, Aflatoxin and Heavy Metals Composition of Dried Fish from Idi-ape Markets in Ilorin, Nigeria

Mycological, Aflatoxin and Heavy Metals Composition of Dried Fish from Idi-ape Markets in Ilorin, Nigeria

Mechanisms of Health Improvement by Lactiplantibacillus plantarum Based on Animal and Human Trials: A Review

Spatio-temporal evolution, exposure and health risk assessment of potentially toxic elements in China’s farmland soils

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