Metallosis associated with a stable titanium-alloy femoral component in total hip replacement. A case report.

Black, Jonathan; Sherk, Henry H.; Bonini, Julius; Rostoker, W.; Schajowicz, Fritz; Jo, Galante

doi:10.2106/00004623-199072010-00021

Cited by 181 publications

(66 citation statements)

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“…Metallosis is defined as aseptic fibrosis, local necrosis, or loosening of a device secondary to metal corrosion and release of wear debris (Black et al, 1990;Bullough, 1994). It involves deposition and build-up of metallic debris in the soft tissues of the body.…”

Section: Peri-implant Mucosa Responsementioning

confidence: 99%

Systemic and Local Tissue Response to Titanium Corrosion

Olmedo¹,

Tasat²,

Duffó³

et al. 2012

Pitting Corrosion

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Section: Peri-implant Mucosa Responsementioning

confidence: 99%

Systemic and Local Tissue Response to Titanium Corrosion

Olmedo¹,

Tasat²,

Duffó³

et al. 2012

Pitting Corrosion

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“…Although titanium implants are considered as highly corrosion resistant materials for applications in body fluids, the determination of their corrosion rate is of great importance. Indeed, some studies indicated that titanium release in the organism, even at low levels, can lead from local discoloration of the tissues to serious inflammatory reactions [9][10] . The aim of the present work was to study the corrosion behavior of three titanium dental implants purchased on the Brazilian market in artificial saliva, using open-circuit potential measurements, electrochemical impedance spectroscopy and potentiodynamic polarization.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical behavior of three CP titanium dental implants in artificial saliva

Kadowaki¹,

Martínez²,

Robin³

2009

Mat. Res.

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The electrochemical behavior of three titanium dental implants purchased on the Brazilian market was evaluated in artificial saliva using open-circuit potential measurements, electrochemical impedance spectroscopy and potentiodynamic polarization. The three implants are passive in this medium but their corrosion resistance and the stability of their passive oxide films are quite different. Although the three implants were made of commercially pure grade titanium, their corrosion current densities and passive current densities were shown to differ from one to two orders of magnitude

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“…t has been established that serum metal levels are increased following primary total hip arthroplasty with all types of femoral head-acetabular liner articulation couples [1][2][3][4] . In recent years there has been mounting concern regarding adverse local and systemic effects of elevated metal levels from total joint replacement components.…”

mentioning

confidence: 99%

“…Studies have documented local softtissue reactions [5][6][7][8] , pseudotumor formation 6 , systemic effects 7 , and end-organ deposition 9 with elevated serum metal concentrations from metal-on-metal total hip replacements 8 . However, increased serum metal levels are not unique to metal-on-metal bearings, and other implant devices may present with elevated metal levels and adverse local and remote tissue responses 1,2,9,10 . All metallic components of joint replacements are subject to electrochemical corrosion, potentially resulting in the formation of chemically active metal degradation products 4 .…”

mentioning

confidence: 99%

Ten-Year Outcome of Serum Metal Ion Levels After Primary Total Hip Arthroplasty

Levine

Hsu

Skipor

et al. 2013

The Journal of Bone and Joint Surgery

101

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We previously reported on the metal ion concentrations of cobalt, chromium, and titanium that were found in the serum of patients three years after they had undergone primary total hip arthroplasty as compared with the concentrations found in the serum of control patients who did not have an implant. This study is a concise update on the serum metal levels found in a cohort of these patients ten years after the time of hip implantation. Of the original seventy-five subjects, metal ion levels were available for forty patients (53%). Ten patients (hybrid group) had received a hybrid total hip replacement that consisted of a modular cobalt-alloy femoral stem with a cobalt-alloy femoral head that had been inserted with cement and a titanium acetabular socket that had been inserted without cement. Nine patients (cobalt-chromium [CoCr] group) had received an implant with an extensively porous-coated modular cobalt-alloy femoral stem and femoral head along with a titanium acetabular socket; the femoral and acetabular components had each been inserted without cement. Eight patients (titanium group) had undergone insertion of a proximally porous-coated modular titanium-alloy femoral stem with a cobaltalloy femoral head and a titanium acetabular socket; the femoral and acetabular components had each been inserted without cement. Thirteen patients (control group) from the original control group of patients who had not received an implant served as control subjects. Serum metal levels were measured with use of high-resolution sector field inductively coupled plasma mass spectrometry. The hybrid total hip arthroplasty group had mean cobalt levels that were 3.2 times higher at 120 months than they were at baseline, and the cobalt levels in that group were significantly higher than those in the titanium total hip arthroplasty group at thirty-six, sixty, eighty-four, ninety-six, and 120 months (p < 0.01). The hybrid group had mean chromium levels that were 3.9 times higher at 120 months than they were at baseline, and the CoCr total hip arthroplasty group had chromium levels that were 3.6 times higher at 120 months than they were at baseline. The serum titanium levels were higher in the titanium group at all follow-up time intervals as compared with the levels in all other groups, and the level in the titanium group at 120 months was eighteen times higher than it was at baseline (p < 0.01). Patients with well-functioning primary metal-on-polyethylene total hip replacements had elevated serum metal levels for as many as ten years postoperatively. Furthermore, metal release at the modular femoral head-neck junctions, rather than passive dissolution from porous ingrowth surfaces, was likely the dominant source of serum cobalt and chromium.continued

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Metallosis associated with a stable titanium-alloy femoral component in total hip replacement. A case report.

Cited by 181 publications

References 0 publications

Systemic and Local Tissue Response to Titanium Corrosion

Systemic and Local Tissue Response to Titanium Corrosion

Electrochemical behavior of three CP titanium dental implants in artificial saliva

Ten-Year Outcome of Serum Metal Ion Levels After Primary Total Hip Arthroplasty

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