Metaplastic Breast Carcinoma: Acase Report

Abstract

Metaplastic breast carcinoma is defined as a heterogeneous group of invasive breast cancercharacterized by differentiation of the neoplastic epithelium into squamous or mesenchymalcells with differentiation into spindle, chondroid, bone or other cells. It is a rare malignanttumor that represents lessthan 1% of breast cancers. It is an aggressive tumor, with a poorprognosis and resistant to chemotherapy.We report a case of metaplastic breast carcinoma, in order to discuss the epidemiological,clinical and histopathological particularities with a review of the literature.This caseconcerned a52-year-old woman with a nodule in the upper outer quadrant of the right breast,with a history of excision of a cystic papilloma on the same site, classified ACR4 onmammography. Histological and immunohistochemical examinationhad concludedametaplastic carcinoma.