Metastatic-directed therapy using PSMA-PET/CT at PSA relapse

Lilleby, Oscar; Hernes, Eivor; Lilleby, Wolfgang

doi:10.1016/j.eucr.2019.100992

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…The study found a longer ADT-free survival with MDT than surveillance alone. Only very few studies have been published on the results of MDT based on results from PSMA PET/CT [ 140 ]. Mazzola et al compared the impact of 18 F-choline and 68 Ga-PSMA PET/CT-guided MDT with stereotactic body radiotherapy (SBRT) in patients with castration-sensitive oligorecurrent PCa [ 141 ].…”

Section: Clinical Applicationmentioning

confidence: 99%

The Role of PSMA PET/CT in the Primary Diagnosis and Follow-Up of Prostate Cancer—A Practical Clinical Review

Lisney

Leitsmann

Strauß

et al. 2022

Cancers

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The importance of PSMA PET/CT in both primary diagnostics and prostate cancer recurrence has grown steadily since its introduction more than a decade ago. Over the past years, a vast amount of data have been published on the diagnostic accuracy and the impact of PSMA PET/CT on patient management. Nevertheless, a large heterogeneity between studies has made reaching a consensus difficult; this review aims to provide a comprehensive clinical review of the available scientific literature, covering the currently known data on physiological and pathological PSMA expression, influencing factors, the differences and pitfalls of various tracers, as well as the clinical implications in initial TNM-staging and in the situation of biochemical recurrence. This review has the objective of providing a practical clinical overview of the advantages and disadvantages of the examination in various clinical situations and the body of knowledge available, as well as open questions still requiring further research.

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Section: Clinical Applicationmentioning

confidence: 99%