Metastatic Subcutaneous Abscess Caused by Nocardia brasiliensis.

Baba, Yukari; Inoue, Yasushi; Tajima, Kimiko; R, Fukushiro; Ikeda, Shigeo

doi:10.2336/nishinihonhifu.57.1003

Cited by 2 publications

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References 4 publications

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“…It has been reported that most cases of disseminated subcutaneous nocardial abscess occur in patients in an immunodeficient state (5,6). The primary lesion of secondary cutaneous nocardiosis commonly develops in the lung by trans-airway infection, and the microorganisms are then hematogenously disseminated to various organs, including the brain, liver, kidney, or skin.…”

Section: Discussionmentioning

confidence: 99%

Subcutaneous Nocardial Abscesses in a Patient with Bullous Pemphigoid during Immunosuppressive Therapy: Report of a Case and Review of the Japanese Literature

Kakurai

Hiraga

Yamada

et al. 1999

The Journal of Dermatology

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We describe a rare case of multiple, subcutaneous nocardial abscesses. A 67-year-old Japanese male with bullous pemphigoid was admitted to our hospital, and systemic prednisolone and double filtration plasmapheresis were administered. During the combination treatment, he noted a solitary subcutaneous nodule on the right upper arm. The lesions gradually increased in number and disseminated. The microbial diagnosis was thought to be a Nocardia species. Administration of combination chemotherapy with minocycline and diamino-diphenyl sulfone failed to eliminate the nodules completely, so he was treated with daily injection of amikacin sulfate into the nodules. The lesions dramatically responded to this therapy and resolved in four weeks.

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Section: Discussionmentioning

confidence: 99%

Subcutaneous Nocardial Abscesses in a Patient with Bullous Pemphigoid during Immunosuppressive Therapy: Report of a Case and Review of the Japanese Literature

Kakurai

Hiraga

Yamada

et al. 1999

The Journal of Dermatology

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Nocardia brasiliensis Infection Seen on Grafted Skin of the Dorsum of a Foot.

Maeda¹,

Sato²,

Tozaki³

et al. 2001

Jpn J Med Mycol

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For the past 4 years a 23 y-old female has noticed erythema on the dorsum of the right foot, where skin was grafted due to a traffic accident 20 years ago. She visited the Department of Dermatology of Gifu Prefectural Hospital on Oct. 19, 1998; her general health was good. Physical examination disclosed a swelling with erythema, papules and pustules on the dorsum of the right foot. The results of routine laboratory investigations were within normal limits except for the white blood cell count (11,300/mm3), blood sediment rate (25mm/hrs), C reactive protein (1.21) and rheumatoid factor (X16.6). Several yellowish and verrucous or wrinkled colonies were grown on Sabouraud's agar culture from the biopsied specimen of the foot. Histopathological features showed epidermal hyperplasia with elongation of rete ridges and granulomatous changes in the dermis; many mononuclear and giant cells were present, and several positive fine filamentous and irregularly branching structures with PAS and Grocott stains were seen in the granulomatous nests. Both clinical and histopathological features led to speculation of Nocardia infection, and Nocardia brasiliensis was determined. The patient was treated by surgical total resection including the grafted skin. Although a soybean-sized nodule was seen on the border of the skin-graft of the foot three months later, there was no recurrence after the local resection.

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Metastatic Subcutaneous Abscess Caused by Nocardia brasiliensis.

Cited by 2 publications

References 4 publications

Subcutaneous Nocardial Abscesses in a Patient with Bullous Pemphigoid during Immunosuppressive Therapy: Report of a Case and Review of the Japanese Literature

Subcutaneous Nocardial Abscesses in a Patient with Bullous Pemphigoid during Immunosuppressive Therapy: Report of a Case and Review of the Japanese Literature

Nocardia brasiliensis Infection Seen on Grafted Skin of the Dorsum of a Foot.

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