Metformin as a protective agent against natural or chemical toxicities: a comprehensive review on drug repositioning

Protection by metformin against severe Covid-19: An in-depth mechanistic analysis

“…Many in vitro and animal studies have shown that MET protects against mortality or cell death in various disease situations (reviewed in [105] ) or following exposure to toxins [106] . An impressive example is the spectacular survival of animals submitted to haemorrhagic shock and treated with MET upon reperfusion [107] .…”