Methane-derived electrochemical sensor for determination of paracetamol and diquat

S. de Sá, Bruna; S. Stefano, Jéssica; G. e Silva, Luiz Ricardo; M. Perfecto, Tarcísio; Mazon, Talita; Volanti, Diogo P.; C. Janegitz, Bruno; Ribeiro, Caue

doi:10.1016/j.matchemphys.2024.129025

Cited by 2 publications

(1 citation statement)

References 51 publications

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“…It is challenging to transport and has no long-term stability. Therefore, nonenzymatic electrochemical sensing of C 6 H 12 O 6 and H 2 O 2 is accurate and suitable because they are easy to transport and handle. − …”

Section: Introductionmentioning

confidence: 99%

Designing Nanocomposite-Based Electrochemical Biosensors for Diabetes Mellitus Detection: A Review

Guo,

Wang,

et al. 2024

ACS Omega

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This review will unveil the development of a new generation of electrochemical sensors utilizing a transition-metal-oxide-based nanocomposite with varying morphology. There has been considerable discussion on the role of transition metal oxide-based nanocomposite, including iron, nickel, copper, cobalt, zinc, platinum, manganese, conducting polymers, and their composites, in electrochemical and biosensing applications. Utilizing these materials to detect glucose and hydrogen peroxide selectively and sensitively with the correct chemical functionalization is possible. These transition metals and their oxide nanoparticles offer a potential method for electrode modification in sensors. Nanotechnology has made it feasible to develop nanostructured materials for glucose and H 2 O 2 biosensor applications. Highly sensitive and selective biosensors with a low detection limit can detect biomolecules at nanomolar to picomolar (10 −9 to 10 −12 molar) concentrations to assess physiological and metabolic parameters. By mixing carbon-based materials (graphene oxide) with inorganic nanoparticles, nanocomposite biosensor devices with increased sensitivity can be made using semiconducting nanoparticles, quantum dots, organic polymers, and biomolecules.

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Section: Introductionmentioning

confidence: 99%

Designing Nanocomposite-Based Electrochemical Biosensors for Diabetes Mellitus Detection: A Review

Guo,

Wang,

et al. 2024

ACS Omega

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Development of an Electrochemical Paper-Based Device Modified with Functionalized Biochar for the Screening of Paracetamol in Substandard Medicines

Silva,

Barreto,

Sousa

et al. 2024

Molecules

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The global prevalence of counterfeit and low-quality pharmaceuticals poses significant health risks and challenges in medical treatments, creating a need for rapid and reliable drug screening technologies. This study introduces a cost-effective electrochemical paper-based device (ePAD) modified with functionalized bamboo-derived biochar (BCF) for the detection of paracetamol in substandard medicines. The sensor was fabricated using a custom 3D-printed stencil in PLA, designed for efficient production, and a 60:40 (m/m) graphite (GR) and glass varnish (GV) conductive ink, resulting in a robust and sensitive platform. The electroactive area of the ePAD/BCF sensor was determined as 0.37 cm2. Characterization via SEM and cyclic voltammetry (CV) verified its structural and electrochemical stability. The sensor demonstrated linear detection of paracetamol from 5.0 to 60.0 µmol L−1 with a detection limit of 3.50 µmol L−1. Interference studies showed high selectivity, with recoveries of over 90%, and the sensor successfully quantified paracetamol in commercial analgesic and anti-flu samples. This sustainable, bamboo-based ePAD offers a promising solution for rapid on-site pharmaceutical quality control, with significant potential to enhance drug screening accuracy.

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Methane-derived electrochemical sensor for determination of paracetamol and diquat

Cited by 2 publications

References 51 publications

Designing Nanocomposite-Based Electrochemical Biosensors for Diabetes Mellitus Detection: A Review

Designing Nanocomposite-Based Electrochemical Biosensors for Diabetes Mellitus Detection: A Review

Development of an Electrochemical Paper-Based Device Modified with Functionalized Biochar for the Screening of Paracetamol in Substandard Medicines

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