Method of preparation and evaluation of Green synthesis silver nanoparticle: An updated review

Chintamani, Ravindra; Salunkhe, Kishor S.; Chavan, Machindra J.

doi:10.22376/ijpbs.2018.9.2.p69-84

Cited by 13 publications

(14 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As an important trace element in animals and humans, Se plays an important role in maintaining normal physiological functions of the brain and has a neuroprotective effect, and some selenoproteins are involved in the regulation of neurodegenerative disorders. It is known that Se metabolism in the brain differs from metabolism in other organs, because it is predominantly preserved in the brain in the presence of selenium deficiency [ 75 , 76 ]. In recent decades, the role of SeNP in neurological diseases has been actively studied ( Table 2 , Figure 2 ), since neurons are especially vulnerable to damage caused by oxidative stress for a number of reasons, such as high oxygen consumption (approximately 25% of total body consumption), the presence of a large amount of polyunsaturated fatty acids, and low levels of antioxidant enzymes [ 77 , 78 , 79 ].…”

Section: The Role Of Senp In Medicine and Human Healthmentioning

confidence: 99%

“…Oxidative stress is one of the main factors in the pathogenesis of many neurological diseases; therefore, natural antioxidants are often used for their treatment, but they have low efficiency [ 75 , 76 ], and thus the use of antioxidants in the form of nanosized particles is becoming increasingly popular. However, it has been shown that nanoparticles are most often oxidizing agents; they can cause damage to neurons and impair the cognitive functions of the brain in Alzheimer’s disease (AD) patients [ 105 , 106 , 107 , 108 , 109 ].…”

Section: The Role Of Senp In Medicine and Human Healthmentioning

confidence: 99%

See 1 more Smart Citation

Therapeutic Potential and Main Methods of Obtaining Selenium Nanoparticles

Varlamova

Turovsky

Блинова

2021

IJMS

View full text Add to dashboard Cite

This review presents the latest data on the importance of selenium nanoparticles in human health, their use in medicine, and the main known methods of their production by various methods. In recent years, a multifaceted study of nanoscale complexes in medicine, including selenium nanoparticles, has become very important in view of a number of positive features that make it possible to create new drugs based on them or significantly improve the properties of existing drugs. It is known that selenium is an essential trace element that is part of key antioxidant enzymes. In mammals, there are 25 selenoproteins, in which selenium is a key component of the active site. The important role of selenium in human health has been repeatedly proven by several hundred works in the past few decades; in recent years, the study of selenium nanocomplexes has become the focus of researchers. A large amount of accumulated data requires generalization and systematization in order to improve understanding of the key mechanisms and prospects for the use of selenium nanoparticles in medicine, which is the purpose of this review.

show abstract

Section: The Role Of Senp In Medicine and Human Healthmentioning

confidence: 99%

Section: The Role Of Senp In Medicine and Human Healthmentioning

confidence: 99%

Therapeutic Potential and Main Methods of Obtaining Selenium Nanoparticles

Varlamova

Turovsky

Блинова

2021

IJMS

View full text Add to dashboard Cite

show abstract

“…Green synthesis of nanomaterials using plant extracts as a furious source of natural compounds like carbohydrates, phenolics, flavonoids, tannins, and alkaloids [ 9 , 10 ] that could act as safe reducing and stabilizing agents in addition to their ability to maintaining aseptic environments throughout the process [ 11 , 12 ]. Therefore, medicinal plants of therapeutic potential could control the dimensions and forms of the biosynthesized nanomaterial [ 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

The Antimicrobial, Antioxidant, and Anticancer Activity of Greenly Synthesized Selenium and Zinc Composite Nanoparticles Using Ephedra aphylla Extract

et al. 2021

View full text Add to dashboard Cite

The current work aimed to synthesize selenium and zinc nanoparticles using the aqueous extract of Ephedra aphylla as a valuable medicinal plant. The prepared nanoparticles were characterized by TEM, zeta potential, and changes in the phytochemical constituents. Hence, the phenolic, flavonoid, and tannin contents were reduced in the case of the prepared samples of nanoparticles than the original values in the aqueous extract. The prepared extract of Ephedra aphylla and its selenium and zinc nanoparticles showed high potency as antioxidant agents as a result of the DPPH• assay. The samples were assessed as anticancer agents against six tumor cells and a normal lung fibroblast (WI-38) cell line. The selenium nanoparticles of Ephedra aphylla extract revealed very strong cytotoxicity against HePG-2 cells (inhibitory concentration (IC50) = 7.56 ± 0.6 µg/mL), HCT-116 cells (IC50 = 10.02 ± 0.9 µg/mL), and HeLa cells (IC50 = 9.23 ± 0.8 µg/mL). The samples were evaluated as antimicrobial agents against bacterial and fungal strains. Thus, selenium nanoparticles showed potent activities against Gram-negative strains (Salmonella typhimurium, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli), Gram-positive strains (Bacillus cereus, Listeria monocytogenes, Staphylococcus aureus, and Staphylococcus epidermidis), and the fungal strain Candida albicans. In conclusion, the preparation of nanoparticles of either selenium or zinc is crucial for improved biological characteristics.

show abstract

“…9,10 Over the past few years, synthesis and characterization of nanoparticles have gained increasing momentum and has immense potential to revolutionize in the biomedical research by developing new and improved products for clinical diagnosis and therapy. 11 Silver has become one of the most universal antimicrobial substances, especially after expanding the surface area of silver particles by nanoengineering. 12,13 Nowadays, great attention was given toward biomedicinerelated assessment of silver nanoparticles (AgNPs), as unconventional antimicrobial agents.…”

Section: Introductionmentioning

confidence: 99%

Combination of Silver Nanoparticles and Vancomycin to Overcome Antibiotic Resistance in Planktonic/Biofilm Cell from Clinical and Animal Source

Mohamed

Mostafa

Mohamed

et al. 2020

Microbial Drug Resistance

View full text Add to dashboard Cite

This study aims to evaluate the prevalence of multidrug-resistant (MDR) and biofilm-forming pathogens from animal source compared to clinical ones. In addition, to assess the antibacterial and antibiofilm activity of silver nanoparticles (AgNPs) alone and/or mixed with vancomycin. Out of 62 bacterial isolates from animal respiratory tract infection (RTI), 50.00% were defined as MDR, while among human ones, 44.00% were MDR. The bacteria Staphylococcus aureus, Pseudomonas aeruginosa, and Streptococcus pneumoniae were the predominant isolated bacteria from both animal and human origin with frequency percentage of 50.00, 22.32, and 18.75, respectively. Among Staph. aureus strains, mecA gene was detected in 60.00% and 61.54% of animal and human isolates, respectively, while mec ALGA251 (mecC) gene was detected in 13.33% and 15.38% of animal and human isolates, respectively. Biofilm formation ability among animal isolates was 83.87%, while among human ones was 86.00%. AgNPs were effective in inhibiting planktonic cells with minimal inhibitory concentration (MIC) values (0.625-10 mg/mL), as well as eradicating biofilm with minimal biofilm eradication concentration values (1.25-10 mg/mL). Noticeable low MIC of AgNPs was required for the isolates from animal source (0.625-5 mg/mL) compared to clinical ones (0.625-10 mg/mL). Remarkable reduction in AgNP effective concentration was observed after combination with 1/4 MIC of vancomycin with minimum recorded concentration of 0.08 mg/mL. In conclusion, the prevalence of MDR among RT pathogens was recorded with high ability to produce biofilm and virulence factors from both animal and human pathogens. AgNPs showed strong antibacterial and antibiofilm activity alone and mixed with vancomycin, with up to fourfold reduction of AgNP inhibitory dose.

show abstract

Method of preparation and evaluation of Green synthesis silver nanoparticle: An updated review

Cited by 13 publications

References 0 publications

Therapeutic Potential and Main Methods of Obtaining Selenium Nanoparticles

Therapeutic Potential and Main Methods of Obtaining Selenium Nanoparticles

The Antimicrobial, Antioxidant, and Anticancer Activity of Greenly Synthesized Selenium and Zinc Composite Nanoparticles Using Ephedra aphylla Extract

Combination of Silver Nanoparticles and Vancomycin to Overcome Antibiotic Resistance in Planktonic/Biofilm Cell from Clinical and Animal Source

Contact Info

Product

Resources

About