The purpose of the article is to study the peculiarities of the management of foreign economic activity of enterprises in current conditions of sustainable development. To achieve the goal of the article, in the study, the following scientific methods are used, namely: analysis and synthesis - to determine approaches to understanding the concept of foreign economic activity and levels of its implementation; statistical - to form the indicators that characterize the state of foreign economic activity in Ukraine; grouping - to obtain groups of regions according to the level of foreign trade turnover; cartographic - to visualize the received groups of regions on the indicators of foreign economic activity; graphic - to visualize the system of foreign economic activity in terms of the need to achieve the stability of regions, enterprises as a leading subject of foreign economic activity and the peculiarities of foreign economic activity of the enterprise in modern conditions. Within the article, the factors of external and internal environment, on which depends the effectiveness of foreign economic activity, are considered. The systems of management of foreign economic activity of the enterprise are studied and characterized. Trends of the development and current state of foreign economic activity in the regions of Ukraine are studied. The grouping of the regions of Ukraine according to the activity of conducting foreign economic activity was carried out, with the separation of the leading and the outsider regions. According to the results of the research, the peculiarities of foreign economic activity of enterprises in modern conditions are identified and outlined, among which the following are singled out: spread of integration processes, structural transformations of the international division of labor, strengthening the role of the state in joining the world economic system.