Training a highly qualified internist in residency is a multifaceted task facing the teaching staff of the Kuban State Medical University.The aim of the study was to analyze the long-term experience of training internal medicine physicians (from 2019 to 2022) at the Kuban State Medical University.Conclusion. A developed methodological system for personalized preparation of internists, the integration of theoretical and practical training, the individual work of students with ongoing progress monitoring of each resident, the mentor system, as well as the active use of modern technical equipment, novel methodological techniques, digital and simulation technologies, introduced organizational measures and material incentives for students have made it possible to achieve 100% employment of General Medicine residency graduates of the Kuban State Medical University in recent years.