Methyl Isobutyl Ketone

Methyl isobutyl ketone (MIBK) is one of the most widely produced and used aliphatic ketones worldwide. The one-step MIBK process with no intermediate separation steps using multifunctional catalysts is an important development towards greener organic synthesis and generates tremendous interest among the researcher across the globe. The single step process is facile and more economically viable and has provided opportunity to develop new and improved catalyst systems capable of operating under mild conditions. A widely variety of catalytic systems have been used in one-step process during last three to four decades. The progress in one-pot synthesis of MIBK using different multifunctional catalysts with special reference to layered based catalysts was critically reviewed in this article.

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Methyl Isobutyl Ketone

Abstract: Methyl isobutyl ketone (MIBK) (4‐methyl‐2‐pentanone) is an industrially important solvent and chemical intermediate. The properties, manufacturing technologies, uses, and health, safety, and environmental aspects of MIBK are discussed in this article.

Cited by 3 publications

References 97 publications

Methyl isobutyl ketone (MIBK) induction of α2u-globulin nephropathy in male, but not female rats

Methyl isobutyl ketone (MIBK) induction of α2u-globulin nephropathy in male, but not female rats

Perspectives on New Chemical Regulatory Framework and Research Direction in Korea.

Progress in One-Pot Synthesis of Methyl Isobutyl Ketone Using Multifunctional Layered Based Catalysts

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