Metronidazole for Non-Specific Vaginitis

Bardi, Mirco; Manenti, Giovanna Oriella; Mattioni, D.; Lasala, L.; Evans, B A

doi:10.1016/s0140-6736(80)91467-1

The Lancet

1980

DOI: 10.1016/s0140-6736(80)91467-1

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Metronidazole for Non-Specific Vaginitis

Mirco Bardi

Giovanna Oriella Manenti

D. Mattioni

et al.

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1982

1984

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Cited by 10 publications

References 3 publications

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In vitro activity of seventeen antimicrobial agents againstGardnerella vaginalis

Shanker¹,

Toohey²,

Munro³

1982

Eur. J, Clin. Microbiol.

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The in vitro activity of 17 antimicrobial agents was tested against 25 clinical isolates of Gardnerella vaginalis. Minimum inhibitory concentrations were determined by agar dilution. The isolates were sensitive to penicillin, ampicillin, ticarcillin, piperacillin, cephalothin, cefoxitin, cefotaxime, cefoperazone, N-formimidoyl-thienamycin, chloramphenicol, clindamycin and erythromycin. MIC90 for the beta-lactam antibiotics ranged from 0.12 mg/l for penicillin to 2 mg/l for ticarcillin. Cefoperazone was the most active cephalosporin, inhibiting all isolates at 1.0 mg/l. N-formimidoylthienamycin was the most active of the newer beta-lactam compounds inhibiting all isolates with a concentration of 0.5 mg/l. Clindamycin and erythromycin were highly active, inhibiting all isolates at 0.6 mg/l. Susceptibility to tetracycline, gentamicin, metronidazole and tinidazole varied between strains. All isolates were resistant to rosoxacin. The hydroxy-metabolites of metronidazole and tinidazole were more active than the parent compounds, inhibiting all isolates.

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In vitro activity of seventeen antimicrobial agents againstGardnerella vaginalis

Shanker¹,

Toohey²,

Munro³

1982

Eur. J, Clin. Microbiol.

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A placebo-controlled, double-blind comparison of tinidazole and triple sulfonamide cream for the treatment of nonspecific vaginitis

Piot¹,

Dyck²,

Godts³

et al. 1983

American Journal of Obstetrics and Gynecology

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Response to Naloxone in Septic Shock

Swinburn

Phelan

1982

The Lancet

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Metronidazole for Non-Specific Vaginitis

Cited by 10 publications

References 3 publications

In vitro activity of seventeen antimicrobial agents againstGardnerella vaginalis

In vitro activity of seventeen antimicrobial agents againstGardnerella vaginalis

A placebo-controlled, double-blind comparison of tinidazole and triple sulfonamide cream for the treatment of nonspecific vaginitis

Response to Naloxone in Septic Shock

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