2015
DOI: 10.1053/j.sodo.2015.06.002
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Micro-osteoperforations: Minimally invasive accelerated tooth movement

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Cited by 67 publications
(77 citation statements)
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References 13 publications
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“…Animal studies revealed that micro-osteoperforations significantly stimulate expression of inflammatory markers and increase the number of osteoclasts and bone resorption. The increase in bone remodeling contributes to the rise in both rate and magnitude of tooth movement [4]. In addition to the requirement of additional studies, similar results are reported in clinical trials [4,5].…”
Section: Introductionmentioning
confidence: 57%
See 1 more Smart Citation
“…Animal studies revealed that micro-osteoperforations significantly stimulate expression of inflammatory markers and increase the number of osteoclasts and bone resorption. The increase in bone remodeling contributes to the rise in both rate and magnitude of tooth movement [4]. In addition to the requirement of additional studies, similar results are reported in clinical trials [4,5].…”
Section: Introductionmentioning
confidence: 57%
“…The rate of orthodontic tooth movement is primarily determined by the remodeling of tissues surrounding the roots; this in return is under the control of molecular mechanisms regulating cellular behaviors in the alveolar bone and periodontal ligament [3]. Assuming that the clinician optimized mechanics and cooperation for any patient, the main factor controlling the treatment time and rate will be the patient's biological response to the orthodontic forces [4,5]. Therefore, identifying and controlling the cellular regulators are essential to shorten orthodontic treatment time safely.…”
Section: Introductionmentioning
confidence: 99%
“…The cytokines and chemokines we assayed have an important role in osteoclast recruitment and activation in the PDL in response to orthodontic forces (22,23). To further confirm…”
Section: Increased and Sustained Expression Of Inflammatory Markers Imentioning
confidence: 95%
“…Various clinical techniques were introduced for accelerated orthodontic tooth movement, including local injection of cellular mediators [1], physical or mechanical stimuli [2], and surgically assisted orthodontics [3,4]. The rate of orthodontic tooth movement is under the control of molecular mechanisms regulating cellular behavior in the alveolar bone and in the periodontal ligament [5][6][7]. Therefore, it is essential to identify and control cellular regulators to safely shorten the duration of orthodontic treatment.…”
Section: Innovations In Orthodonticsmentioning
confidence: 99%