Microalbuminuria in Chronic Obstructive Pulmonary Disease with and Without Co-morbidities

Vyas, Hridyanshu; Purohit, Purvi; Dutt, Naveen; Sharma, Praveen

doi:10.1007/s12291-019-0810-1

Cited by 2 publications

(1 citation statement)

References 5 publications

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“…Chronic obstructive pulmonary disease (COPD) is a major public health problem worldwide (Boehm et al , 2019). This degenerative disease is characterized by persistent airflow limitation, so it is associated with morbidity and mortality (Vyas et al , 2019). It incurs high health-care costs and imposes a significant burden in terms of disability and impaired quality of life (Rafaela et al , 2019; Patel et al , 2018).…”

Section: Introductionmentioning

confidence: 99%

Association of dietary quality indices with sleep quality in chronic obstructive pulmonary disease patients

Paknahad

Yazdanpanah

Maracy

et al. 2020

NFS

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Purpose Patients with chronic obstructive pulmonary disease (COPD) suffer from many health problems including poor sleep. This paper aims to evaluate the relationship between diet quality indices (DQIs) and sleep quality in COPD. Design/methodology/approach The current cross-sectional study was carried on 121 COPD patients. Subjective quality of sleep was determined by Pittsburgh Sleep Quality Index (PSQI) and categorized into “poor” and “good” sleep quality. Dietary history was assessed by the DQIs. Disease status was categorized according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) Guidelines. Findings In total, 103 men and 18 women with a mean age of 66.1 ±10.9 were studied. The subjects were categorized into four groups based on GOLD; 3.3% of subjects were at Stage 1, 38% in Stage 2, 38% in Stage 3 and 20.7% in Stage 4. In total, 38% of subjects were good, and 62% were bad sleepers according to PSQI score. There was no significant relationship between the severity of COPD and PSQI score. We observed a significant inverse relation between PSQI total score and Mediterranean diet (MED) scale, Healthy Eating Index (HEI)-2010 and HEI-2005 (p = 0.024, 0.037 and 0.024, respectively) in males. Originality/value This study showed a high prevalence of poor quality of sleep and sleep disturbances among COPD patients. There was an inverse association between PSQI and sleep disorders and DQIs scores in COPD patients. Regardless of the severity of airflow obstruction, poor diet quality may constitute a risk factor for sleep quality.

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Section: Introductionmentioning

confidence: 99%

Association of dietary quality indices with sleep quality in chronic obstructive pulmonary disease patients

Paknahad

Yazdanpanah

Maracy

et al. 2020

NFS

View full text Add to dashboard Cite

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Microalbuminuria on admission for acute exacerbation of COPD as a predictor of all-cause mortality and future exacerbations

Bartziokas

Kyriakopoulos

Dounousi

2021

Postgraduate Medical Journal

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ObjectivesMicroalbuminuria (MAB) is a sensitive biomarker of cardiovascular risk that is directly associated with cardiovascular events and mortality. Recent studies have evaluated the presence of MAB in patients with stable chronic obstructive pulmonary disease (COPD) or hospitalised for acute exacerbation of COPD (AECOPD).MethodsWe evaluated 320 patients admitted for AECOPD in respiratory medicine departments of two tertiary hospitals. On admission, demographic, clinical and laboratory values and COPD severity were assessed. Patients were evaluated monthly for 1 year, recording new AECOPD and death from any cause.ResultsPatients with documented MAB (urinary albumin excretion of 30–300 mg/24 hours) on admission had worse lung function (forced expiratory volume in 1 s, %) (mean (SD) 34.2 (13.6)% vs 61.5 (16.7)%), higher modified Medical Research Council (3.6 (1.2) vs 2.1 (0.8)), lower 6 min walk test (171 (63) vs 366 (104)) and more hospitalisation days (9 (2.8) vs 4.7 (1.9)) (p<0.001 for all comparisons). MAB was also correlated with Global Initiative for Chronic Obstructive Lung Disease 2020 COPD stages (p<0.001). In multivariate regression analysis, MAB was a significant predictor of longer hospitalisation duration (OR 6.847, 95% CI 3.050 to 15.370, p<0.0001). Twelve-month follow-up revealed that patients with MAB experienced more AECOPDs (4.6 (3.6) vs 2.2 (3.5), p<0.0001) and deaths, n (%) (52 (36.6) vs 14 (7.8), p<0.001). Kaplan-Meier survival curves demonstrated that patients with MAB presented with increased mortality, AECOPD and hospitalisation for AECOPD risk at 1 year (p<0.001 for all comparisons).ConclusionsThe presence of MAB on admission for AECOPD was associated with more severe COPD and prolonged hospitalisation, as well as with higher rates of AECOPD and mortality risk at 1-year follow-up.

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Microalbuminuria in Chronic Obstructive Pulmonary Disease with and Without Co-morbidities

Cited by 2 publications

References 5 publications

Association of dietary quality indices with sleep quality in chronic obstructive pulmonary disease patients

Association of dietary quality indices with sleep quality in chronic obstructive pulmonary disease patients

Microalbuminuria on admission for acute exacerbation of COPD as a predictor of all-cause mortality and future exacerbations

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