Microbe Profile: Pseudonocardia: antibiotics for every niche

Abstract

Graphical abstract Scanning electron microscopy (SEM) images of Pseudonocardia sp. (a). Ae707-Ps1 and (b). Ae707-Ps2. These are the two lineages of Pseudonocardia associated with Acromyrmex echinatior leafcutter ants collected in Gamboa, Panama. (c). Four specialised metabolites are shown that are produced by Pseudonocardia strains isolated from diverse ecosystems: they are 9-methoxyrebeccamycin, selvamicin, pseudonochelin and attinimicin. (d). This tree shows a subset of phylogenetic diversity showing strain origin (outer ring colour), genome size (Mb, red box) and number of biosynthetic gene clusters (BGCs, purple box). The specialised metabolites (c) are coloured to match the producing strains, the boxed numbers show the genome size (red) and number of BGCs (purple) (d).