Microbicides: Where are We Now and What Next?

McCormack, Sheena

doi:10.2217/hiv.10.50

Cited by 1 publication

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Microbicides therefore put the power of women's protection against HIV infection into their own hands as they do not require partners' cooperation [2]. Indeed, at the Fifth World AIDS Conference in Vienna, 2010, the CAPRISA 004 investigators reported a 39% reduction in HIV incidence, providing a proof of concept for microbicides [19]. Condoms which contribute at preventing HIV transmission have been assessed [6], while the effect of jointly implementing male circumcision and condom use has been reported [20].…”

Section: Introductionmentioning

confidence: 99%

Potential Impact of Male Circumcision, Condom Use, and Microbicides on the Dynamics of HIV/AIDS

Elias

Tchuenche

2012

ISRN Biomathematics

View full text Add to dashboard Cite

HIV/AIDS remains an important global cause of morbidity and mortality. While medical male circumcision and condom and microbicides use hold great promise for helping to stem the tide of new HIV infections, theoretically providing further evidence of the potential long-term population-level benefit of their combined effects is viable. A deterministic sex-structured model is formulated, the expected lifetime disease reproductive output of an individual (or epidemiological birth) is determined, and the stability of steady states is investigated. To complement HIV treatment with antiretrovirals, which is not yet fully accessible to all those in need, microbicides and nontherapeutic measures such as male circumcision and condoms provide additional potential impact on curtailing the spread of HIV/AIDS.

show abstract