1983
DOI: 10.1177/00220345830620081201
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Microbiologic Effects of SnF2 and NaF Mouthrinses in Subjects with High Caries Activity: Results after One Year

Abstract: Twenty-two adults, considered to have high caries activity, rinsed for one yr with either SnF2 or acidulated NaF mouthrinses. Total colony-forming units and numbers of S. mutans and lactobacilli were estimated from saliva samples. Large reductions were found in the number of recoverable S. mutans in subjects rinsing with SnF2 but not in the NaF group.

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Cited by 18 publications
(6 citation statements)
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“…Although fluoride traditionally has been thought to affect caries through its physiochemical interaction with enamel, evidence exists that fluoride also alters bacterial metabolism at low concentrations and is bactericidal at higher concentrations. [6] While fluoride varnishes, fluoride mouth rinses and oral hygiene instructions have been employed they rely on patient compliance and provide only intermittent protection against decalcification. When bonding with GIC there is no need for pretreatment of enamel with acid as there is chemical bonding of GIC with the tooth and it also releases fluoride into the oral cavity for several months.…”
Section: Introductionmentioning
confidence: 99%
“…Although fluoride traditionally has been thought to affect caries through its physiochemical interaction with enamel, evidence exists that fluoride also alters bacterial metabolism at low concentrations and is bactericidal at higher concentrations. [6] While fluoride varnishes, fluoride mouth rinses and oral hygiene instructions have been employed they rely on patient compliance and provide only intermittent protection against decalcification. When bonding with GIC there is no need for pretreatment of enamel with acid as there is chemical bonding of GIC with the tooth and it also releases fluoride into the oral cavity for several months.…”
Section: Introductionmentioning
confidence: 99%
“…The earliest research on the antibacterial activity of stannous ions and their use in dentistry comes from the 1970s. Initially the studies, led in vivo [11] and in vitro [12], compared the stannous fluoride to previously-used sodium fluoride. The researchers described the much higher antibacterial activity of stannous fluoride.…”
Section: The Mechanisms Of the Antibacterial Activity Of Sn 2+ Ions Ementioning
confidence: 99%
“…Stannous fluoride 0.4% gel is recommended by Veterans Administration dentists for this purpose 64,65 . Research suggests that topical fluoride is effective even in the presence of dental microbial plaque 66–70 …”
Section: Prevention Of Dental Problemsmentioning
confidence: 99%