Microbiological and Histological Picture in Local Cryo Impact on a Suppurating Wound

Abstract

e. In light of the significant perspectives for the use of elements of physical processing factors in the treatment of purulent diseases of soft tissues, spesial attention should be paid of local cryoinfluence in the debridement of purulent wounds. Purpose of the work: to study changes in the histological and microbiological picture during cryo-treatment of a purulent wound model. Material and methods. Superficial purulent wounds of soft tissues were modeled on 40 male Wistar rats. A dynamic microbiological study of wound smears and histological biopsy specimens was performed with cryotherapy and without interfering with the course of the wound process. Results. The treatment with cryotherapy revealed a statistically significant acceleration of the elimination of the pathogen from the wound, the rapid development of fresh connective tissue and the restoration of the microvascular bed, and the activation of the rate of epithelialization. Conclusions. Debridement and the use of local cryoprocessing contributes to the rapid elimination of the pathogen from the wound, activates the processes of granulation and epithelialization. Further clinical study and introduction into practice of local cryotherapy in purulent diseases of soft tissues is substantiated.