Microbiological diagnostic testing in the treatment of periodontal diseases

Loomer, Peter M.

doi:10.1046/j.0906-6713.2002.003424.x

Cited by 115 publications

(127 citation statements)

References 87 publications

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“…There are a number of possible explanations for this inconsistency, including differences in disease status at the sampled site and the method used to detect and estimate the copy numbers of pathogens present (41). Loomer reported that analysis of the overall oral microbiota profile of a patient is more representative when a greater number of sites is sampled (42). Thus, in this study, samples from at least five sites with the deepest pockets were collected and pooled together, which was essential in accurately characterizing subgingival microbiota in its natural niche in the deepest pockets.…”

Section: Discussionmentioning

confidence: 99%

Comparison of nonsurgical periodontal therapy with oral hygiene instruction alone for chronic periodontitis

et al. 2017

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We evaluated changes in clinical variablesand microbiological profiles of periodontopathogens among 56 patients with moderate to severe CP who were randomly assigned to oral hygiene instruction (OHI; n = 28) or nonsurgical periodontal treatment (NSPT; n = 28). Periodontal variables were assessed and subgingival plaque samples were obtained from deep pockets (≥5 mm) at baseline and 3 months after treatment. Real-time polymerase chain reaction was used to quantify Actinobacillus actinomycetemcomitans, Tannerella forsythia, Porphyromonas gingivalis, and Prevotella intermedia. All clinical variables significantly improved in both groups. Improvements in gingival bleeding index (GBI), probing pocket depth (PPD), and periodontal attachment loss (PAL) were significantly greater at 3 months after treatment in the NSPT group. At baseline, the prevalences of all pathogens were high. Significant reductions in microbial count were observed for A. actinomycetemcomitans and T. forsythia (P ≤ 0.05) in the NSPT group. None of the improvements in clinical variables was associated with changes in microbiological profiles. At 3 months after treatment, NSPT was associated with significantly greater improvements in GBI, PPD, and PAL as compared with OHI. A. actinomycetemcomitans and T. forsythia counts were significantly lower in the NSPT group.

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Section: Discussionmentioning

confidence: 99%

Comparison of nonsurgical periodontal therapy with oral hygiene instruction alone for chronic periodontitis

et al. 2017

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“…The findings suggest that different species of periodontal pathogens necessitate different sampling schemes [22]. The outcome of the analysis can further be affected by the method of sample collection [12,19].…”

Section: Samplingmentioning

confidence: 99%

Clinical Relevance of the Advanced Microbiologic and Biochemical Investigations in Periodontal Diagnosis: A Critical Analysis

Grover¹,

Kapoor

Malhotra³

et al. 2014

Journal of Oral Diseases

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New approaches to periodontal diagnosis, including advanced microbiologic, biochemical, and genetic tests, have been shown to provide the clinician with the information not available by traditional means. The purpose of a diagnostic test is to confirm, exclude, classify, or monitor disease to guide treatment. Their clinical value depends on whether the information they provide leads to improved patient outcomes. This can be assessed by randomized trials, which compare patient outcomes from the new diagnostic test versus the old test strategy. Being nonmandatory for marketing approval, such trials are not always feasible because of large sample sizes requirements. So, many diagnostic tests enter the practice without being critically analysed for any additional benefits. Effective diagnosis is just as essential as the selection of effective treatments for the success of periodontal therapy. So, the current paper aims to focus on the practical utility of this rapidly emerging plethora of periodontal diagnostic tools, emphasizing the critical issues surrounding the clinical application of microbiologic and biochemical investigations, employed for periodontal diagnosis.

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“…-increased prognostic value -aids in planning appropriate therapeutic strategy -targeted antibiotic therapy -monitoring of successful periodontal therapy -allows a high level of certainty when expensive interventions such as placing dental implants and prosthetic or orthodontic rehabilitation are necessary [18].…”

Section: Benefits Of Microbiological Diagnosticsmentioning

confidence: 99%

Modern Approach to the Identification and Elimination of Periodontal Infection

2012

Maced J Med Sci

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In global terms, periodontitis is the leading cause of tooth loss, and causes serious aesthetic and functional problems. There are numerous scientific evidence that power periopathogenic microorganisms may have influence on some systemic conditions and diseases. If we add the fact that periimplantitis are caused by identical periopathogenes, management or effective identification and elimination of periodontal inflammation set as imperative in successful periodontal treatment and possible complications locally or systemic, as well as resistance and lifetime of the implants. As a method for quantifying and classification of bacterial species are recommended monitoring of the bacterial micro flora through PCR (polymerase chain reaction) technique. Laser therapy as a supplementary method to classic treatment is strongly emphasized as a new therapeutic option that uses the photo-thermal effect to fight bacterial infection. Air flow -an original method that uses water, air and powder help to destroy the biofilm and remove plaque. Oral application of LAD (Light activated disinfection) therapy influence nascent oxygen breaks down the interaction in biofilm and makes the microorganisms more sensitive to further damage. Finally, the role and use of probiotics as a link between the beneficial oral bacteria species and inflammation.

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Microbiological diagnostic testing in the treatment of periodontal diseases

Cited by 115 publications

References 87 publications

Comparison of nonsurgical periodontal therapy with oral hygiene instruction alone for chronic periodontitis

Comparison of nonsurgical periodontal therapy with oral hygiene instruction alone for chronic periodontitis

Clinical Relevance of the Advanced Microbiologic and Biochemical Investigations in Periodontal Diagnosis: A Critical Analysis

Modern Approach to the Identification and Elimination of Periodontal Infection

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