“…The K L a values were generally highest at t = 12 h of the bioprocess, and had values of K L a = 0.067/s, 0.017/s, 0.043/s and 0.050/s for the M‐0.03, MS‐0.02, MS‐0.03 and MS‐0.04 conditions, respectively. The K L a values obtained were in the lower range of previously reported values for P. pastoris fermentations (0.01–0.3/s; Cunha et al , 2004; Zhang et al , 2005; Isett et al , 2007), probably due to the dimensions of the bioreactor used.…”