Microfabrication, separations, and detection by mass spectrometry on ultrathin-layer chromatography plates prepared via the low-pressure chemical vapor deposition of silicon nitride onto carbon nanotube templates

Kanyal, Supriya S.; Häbe, Tim T.; Cushman, Cody V.; Dhunna, Manan; Roychowdhury, Tuhin; Farnsworth, Paul B.; Morlock, Gertrud E.; Linford, Matthew R.

doi:10.1016/j.chroma.2015.05.053

Cited by 20 publications

(10 citation statements)

References 38 publications

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“…SEM micrographs of CNTs conformally coated with ca. 38 nm layer of Si 3 N 4 and of microfabricated UTLC plates oxidized at 1000°C showing no expansion or distortions of the microfeatures …”

Section: Preparation Of Monolithic Layersmentioning

confidence: 96%

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Recent advances in the preparation of adsorbent layers for thin‐layer chromatography combined with matrix‐assisted laser desorption/ionization mass‐spectrometric detection

Kucherenko

Kanat’eva

Пирогов

et al. 2018

J of Separation Science

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This review is focused on planar chromatography hyphenated with mass-spectrometric detection for analysis of low-molecular-mass solutes. Various kinds of hyphenations are discussed with attention paid to the preparation of thin layer plates suited both for the mass-spectrometric detection of the resolved solutes direct from thin-layer plates and for indirect mass-spectrometric detection of the resolved solutes, performed by scraping, extracting, purifying, and concentrating the analyte from the thin-layer chromatography plate. Plates with monolithic layers are relatively new for thin-layer chromatography but they can successfully be combined with mass-spectrometric technique in a pursuit of comprehensive local sample composition information. Preparation of monolithic layers of different porosity and structure based on organic, inorganic, and composite materials is illustrated together with examples of successful separation and detection of low-molecular-mass solutes by means of matrix-assisted and surface-assisted laser desorption mass spectrometry.

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Section: Preparation Of Monolithic Layersmentioning

confidence: 96%

“…Scanning UTLC‐direct analysis in real time mass spectrometry of the separated lipophilic dye mixture. Dimethyl Yellow (1), Oracet Red G (2), Solvent Blue 35 (3), Sudan Red G (4), Solvent Blue 22 (5), and Oracet Violet 2R (6) …”

Section: Preparation Of Monolithic Layersmentioning

confidence: 99%

Recent advances in the preparation of adsorbent layers for thin‐layer chromatography combined with matrix‐assisted laser desorption/ionization mass‐spectrometric detection

Kucherenko

Kanat’eva

Пирогов

et al. 2018

J of Separation Science

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“…The microfabrication of ultrathin-layer chromatography (UTLC) plates via conformal low-pressure chemical vapor deposition of silicon nitride onto patterned carbon nanotube (CNT) scaffolds, acting as surface templates, has been described by Kanyal et al [ 109 ]. The plates were heated and oxidized to both remove the CNTs and convert Si 3 N 4 into silica; finally, the plates were hydroxylated in aqueous ammonium hydroxide.…”

Section: Materials For Spray-based Ionization Techniquesmentioning

confidence: 99%

MS-Based Analytical Techniques: Advances in Spray-Based Methods and EI-LC-MS Applications

Bianchi

Riboni

Termopoli³

et al. 2018

Journal of Analytical Methods in Chemistry

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Mass spectrometry is the most powerful technique for the detection and identification of organic compounds. It can provide molecular weight information and a wealth of structural details that give a unique fingerprint for each analyte. Due to these characteristics, mass spectrometry-based analytical methods are showing an increasing interest in the scientific community, especially in food safety, environmental, and forensic investigation areas where the simultaneous detection of targeted and nontargeted compounds represents a key factor. In addition, safety risks can be identified at the early stage through online and real-time analytical methodologies. In this context, several efforts have been made to achieve analytical instrumentation able to perform real-time analysis in the native environment of samples and to generate highly informative spectra. This review article provides a survey of some instrumental innovations and their applications with particular attention to spray-based MS methods and food analysis issues. The survey will attempt to cover the state of the art from 2012 up to 2017.

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“…ID‐Cube and modified solid‐phase microextraction (SPME) . In addition to DART, other ambient ionization techniques have been used to collect MS data from (HP)TLC layers, mainly desorption electrospray ionization (DESI) and plasma‐assisted multi‐wavelength laser desorption ionization (PAMLDI) …”

mentioning

confidence: 99%

“…The spatial resolution at full width at half maximum was determined to be 0.8 mm and the scan lane width to be 3 mm . This optimized system was used to scan UTLC and HPTLC tracks to identify lipophilic food dyes and antibacterial compounds of essential oil …”

mentioning

confidence: 99%

Improved desorption/ionization and ion transmission in surface scanning by direct analysis in real time mass spectrometry

Häbe

Morlock

2015

Rapid Comm Mass Spectrometry

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The desorption strength, ionization efficacy and ion transmission were improved significantly giving increased detectability using this further modified DART-MS interface with reduced cap length and optimum transfer tube geometry. The resolution was comparable with state-of-the-art densitometry. With this setup, reliable HPTLC surface scanning is possible, even for substance amounts in the low-nanogram range.

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Microfabrication, separations, and detection by mass spectrometry on ultrathin-layer chromatography plates prepared via the low-pressure chemical vapor deposition of silicon nitride onto carbon nanotube templates

Cited by 20 publications

References 38 publications

Recent advances in the preparation of adsorbent layers for thin‐layer chromatography combined with matrix‐assisted laser desorption/ionization mass‐spectrometric detection

Recent advances in the preparation of adsorbent layers for thin‐layer chromatography combined with matrix‐assisted laser desorption/ionization mass‐spectrometric detection

MS-Based Analytical Techniques: Advances in Spray-Based Methods and EI-LC-MS Applications

Improved desorption/ionization and ion transmission in surface scanning by direct analysis in real time mass spectrometry

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