Micronucleus test in peripheral blood of rats treated with hyperbaric oxygen after subtotal splenectomy preserving the lower pole

Paulo, Marcela Souza Lima; Souza, Ingryd Fortes; Wandekoken, Kethleen Gomes; Silva, Karina Balestreiro; Dutra, Jean Carlos Vencioneck; Freitas, Josivany Valério de; Stegmiller, Nataly Pescinalli; Pimassoni, Lucia Helena Sagrillo; Batitucci, Maria do Carmo Pimentel; Paulo, Danilo Nagib Salomão; Errera, Flávia Imbroisi Valle

doi:10.1590/s0102-865020150040000005

Cited by 2 publications

(1 citation statement)

References 26 publications

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“…A more current study still deals with subtotal splenectomy with preservation of the lower pole in patients with Hodgkin’s lymphoma 12 . Other studies on subtotal splenectomy with preservation of the lower pole in last five years have been published 13 - 14 .…”

Section: Introductionmentioning

confidence: 99%

Macro and microscopic comparison of the upper pole of the spleen with the lower pole in partial splenectomy

et al. 2020

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Purpose To evaluate the viability of the upper (UP) and lower pole (LP) of the spleen from a macro and microscopic point of view, after subtotal splenectomy with preservation (SSP) of the UP and the LP. Methods Seventeen male Wistar rats, two months old, were submitted to SSPUP and SSPLP and 5 to simulated operation (SG). After 80 days, the rats were euthanized, and the remaining LP and UP and intact spleens were evaluated macroscopically and microscopically. Results Two rats died during the operation. Macroscopic analysis showed that in 15 LP, one of them was not viable and in 15 UP and in 5 spleens in the SG, all were viable. In the statistical analysis, there was no difference in relation to viability. The LP and UP analyzed showed variation. As for the length, the UP increased significantly; however, in relation to the width, there was a significant increase in the LP in relation to the UP. In addition, the weight of the UP was significantly greater than that of the LP. Microscopic analysis attested viability of the splenic remnants. Conclusion There was no significant difference regarding the viability of UP and LP, in macroscopy and microscopy.

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Section: Introductionmentioning

confidence: 99%

Macro and microscopic comparison of the upper pole of the spleen with the lower pole in partial splenectomy

et al. 2020

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Assessment of water quality and genotoxic impact by toxic metals in Geophagus brasiliensis

et al. 2016

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This study used the pearl cichlid Geophagus brasiliensis as a bioindicator to survey the health of the aquatic environment on four sites (P1, P2, P3 and P4) of the Mumbuca stream located at Monte Carmelo/MG, Brazil. The selection of different sites was made with reference to the gradient of urban activity and via physicochemical and biological evaluation of water quality and genotoxicity. The water quality index was classified as 'good' for P1 and P4, regular in P2 and 'poor' for P3. The micronuclei (MN) frequency obtained from blood analysis was in agreement with the water quality, such that the higher values of MN were detected in sites evaluated as poor. Water degradation conditions worsen according to the flow of the stream over the sites P1, P2 and P3, but for site P4, located after the Monte Carmelo Sewage Treatment Plant, improvements in the micronuclei frequency are detected. Our results showed high levels of potentially toxic metals (chromium, lead, aluminum and nickel) in specific stream sites (P2 and P3). We suggest that the micronuclei induction in G. brasiliensis could be due to the presence of these compounds.

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Micronucleus test in peripheral blood of rats treated with hyperbaric oxygen after subtotal splenectomy preserving the lower pole

Cited by 2 publications

References 26 publications

Macro and microscopic comparison of the upper pole of the spleen with the lower pole in partial splenectomy

Macro and microscopic comparison of the upper pole of the spleen with the lower pole in partial splenectomy

Assessment of water quality and genotoxic impact by toxic metals in Geophagus brasiliensis

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