Microparticles and multi-unit systems for advanced drug delivery

Kállai-Szabó, Nikolett; Farkas, Dóra; Lengyel, Miléna; Basa, Bálint; Fleck, Christian; Antal, István

doi:10.1016/j.ejps.2024.106704

Cited by 4 publications

(1 citation statement)

References 154 publications

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“…Polymer microspheres offer various administration routes, including subcutaneous injection, intra-tumor injection, or inhalation as agents for pulmonary delivery. Furthermore, they provide protection to the drug against environmental factors that could lead to inactivation [ 9 ]. Based on the material used for their construction, polymer microspheres are categorized as biodegradable or non-biodegradable [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Polymer Microspheres and Their Application in Cancer Diagnosis and Treatment

Zhai,

Wu,

Liao

et al. 2024

IJMS

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Cancer is a significant global public health issue with increasing morbidity and mortality rates. To address this challenge, novel drug carriers such as nano-materials, liposomes, hydrogels, fibers, and microspheres have been extensively researched and utilized in oncology. Among them, polymer microspheres are gaining popularity due to their ease of preparation, excellent performance, biocompatibility, and drug-release capabilities. This paper categorizes commonly used materials for polymer microsphere preparation, summarizes various preparation methods (emulsification, phase separation, spray drying, electrospray, microfluidics, and membrane emulsification), and reviews the applications of polymer microspheres in cancer diagnosis, therapy, and postoperative care. The current status and future development directions of polymer microspheres in cancer treatment are analyzed, highlighting their importance and potential for improving patient outcomes.

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Section: Introductionmentioning

confidence: 99%

Polymer Microspheres and Their Application in Cancer Diagnosis and Treatment

Zhai,

Wu,

Liao

et al. 2024

IJMS

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Innovative Pharmaceutical Techniques for Paediatric Dosage Forms: A Systematic Review on 3D Printing, Prilling/Vibration and Microfluidic Platform

Racaniello,

Silvestri,

Pistone

et al. 2024

Journal of Pharmaceutical Sciences

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Biocompatible Tablet Film Coatings for Active Pharmaceutical Ingredients

Navabhatra,

Yingngam

2024

Medical Applications for Biocompatible Surfaces and Coatings

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In the pharmaceutical industry, the process of coating tablets with active pharmaceutical ingredients (APIs) poses significant challenges related to biocompatibility and drug efficacy. Traditional coatings often have limitations in terms of their compatibility with the human body, which can lead to decreased bioavailability and adverse reactions. This chapter aims to address these challenges by focusing on the development of biocompatible tablet film coatings that are specifically designed to deliver APIs while also ensuring safety and enhancing patient compliance. The chapter explores the formulation, characteristics, and benefits of these coatings, with a particular emphasis on how they improve drug solubility, stability, and controlled release, all of which are essential for achieving desired therapeutic outcomes. Additionally, this chapter discusses the selection of biocompatible materials, innovative coating techniques, and methods for evaluating their effectiveness and safety. The impact of film coatings on drug release kinetics, bioavailability, and patient acceptability is also analysed. Moreover, the chapter sheds light on current trends and technological advancements in this exciting field. In conclusion, biocompatible tablet film coatings represent a significant advancement in pharmaceutical technology, offering a promising approach to enhance drug formulations, improve patient outcomes, and minimise adverse reactions. Biocompatible film coatings play a crucial role in the development of modern pharmaceuticals. Future research should focus on exploring novel biodegradable polymers and advanced biocompatible agents as potential coating materials.

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Microparticles and multi-unit systems for advanced drug delivery

Cited by 4 publications

References 154 publications

Polymer Microspheres and Their Application in Cancer Diagnosis and Treatment

Polymer Microspheres and Their Application in Cancer Diagnosis and Treatment

Innovative Pharmaceutical Techniques for Paediatric Dosage Forms: A Systematic Review on 3D Printing, Prilling/Vibration and Microfluidic Platform

Biocompatible Tablet Film Coatings for Active Pharmaceutical Ingredients

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