Microplastics induced endoplasmic reticulum stress to format an inflammation and cell death in hepatocytes of carp (Cyprinus carpio)

Cui, Jie; Zhu, Mengran; Sun, Xiaoran; Yang, Jie; Guo, Mengyao

doi:10.1016/j.aquatox.2024.106870

Cited by 7 publications

(2 citation statements)

References 80 publications

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“…24 Meanwhile, activation of the NF-κB P65 pathway can inhibit Bcl-2, promote Bax expression, activate caspase-9,-7,-3 and further promote apoptosis. 25 CAT, GSH and T-SOD maintain the balance between oxidation and antioxidation in vivo and are classic antioxidant systems. 26 The MDA levels were significantly increased in the TBBPA-treated group, whereas the T-AOC, CAT, GSH and T-SOD levels were significantly decreased, and the addition of GTP resulted in a decrease in MDA levels and a significant increase in T-AOC, CAT, GSH and T-SOD levels, and the same results were obtained in the in vitro experiments, and our results confirm that GTP, like the antioxidant NAC, attenuates TBBPA-induced oxidative stress in mouse lungs and A549 cells, thus reducing the damage of TBBPA on mouse lungs and A549 cells.…”

Section: Discussionmentioning

confidence: 99%

Green tea polyphenols inhibit TBBPA-induced lung injury via enhancing antioxidant capacity and modulating the NF-κB pathway in mice

Lv,

Wang,

Geng

et al. 2024

Food Funct.

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Section: Discussionmentioning

confidence: 99%

Green tea polyphenols inhibit TBBPA-induced lung injury via enhancing antioxidant capacity and modulating the NF-κB pathway in mice

Lv,

Wang,

Geng

et al. 2024

Food Funct.

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“…The major cellular and physiological changes and damages induced by MPs. Stock et al, 2021;Zeng et al, 2024) and in vivo studies, primarily in marine creatures (Cui et al, 2024;Jian et al, 2024;Oliviero et al, 2019;Primpke et al, 2024) and some on rodents (Kuang et al, 2024;Kusma et al, 2024;Sun et al, 2024;Vlacil et al, 2021;.…”

Section: Potential Effects Of Mps On Health Issuesmentioning

confidence: 99%

Prevalence of environmental microplastics in Taiwan and its impact on the seafood safety: An integrative review

Lin,

Wu,

Lin

2024

Journal of Food Safety

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Human activity has led to microplastic contamination throughout the marine environment. As a result of widespread contamination, microplastics are ingested by many species of wildlife, including fish, cephalopods, and shellfish. Taiwan is surrounded by oceans that offer a rich range of seafood. Taiwanese residents can easily acquire seafood as a source of dietary protein. A recent research project by Greenpeace shows that the Taiwanese eat 16,000 microplastic particles per year. There is concern regarding microplastic physical and chemical toxicity, which poses potential health risks to the local community via food chains. Thus, monitoring microplastic contamination in seafood is imperative to provide helpful information for the government and local communities. Efforts should be taken to reduce microplastic pollution at the source to minimize potential effects on ecological and health safety. This review article emphasizes the urgent need for further research on microplastic pollution in Taiwan, highlights the potential challenges to mitigate this emerging environmental threat, and analyzes food safety hazards as well as microplastic contamination in seafood.

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The Effects of Microplastics on Musculoskeletal Disorder; A Narrative Review

Fusagawa,

Youn,

Wilkerson

et al. 2024

Curr Rev Musculoskelet Med

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Purpose of Review The physical health impacts of microplastics have received increasing attention in recent years. However, limited data impedes a full understanding of the internal exposure to microplastics, especially concerning the musculoskeletal system. The purpose of this review is to summarize the recent literature regarding the effects of microplastics on the musculoskeletal system. Recent Findings Microplastics have been shown to cause abnormal endochondral ossification and disrupt the normal function of pre-osteoblasts, osteocyte-like cells, and pre-osteoclasts through gene mutations, endoplasmic reticulum stress induction, and reduced autophagosome formation in bone growth areas. Although there are few reports on their effects on muscle, it has been noted that microplastics inhibit energy and lipid metabolism, decrease type I muscle fiber density, impair muscle angiogenesis, cause muscle atrophy, and increase lipid deposition. Summary Only a few recent studies have shown that microplastics interfere with the normal function of bone growth-related cells and reduce muscle mass and quality. This review underscores the need for further research into other parts of the musculoskeletal system and studies using human tissues at the disease level.

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Microplastics induced endoplasmic reticulum stress to format an inflammation and cell death in hepatocytes of carp (Cyprinus carpio)

Cited by 7 publications

References 80 publications

Green tea polyphenols inhibit TBBPA-induced lung injury via enhancing antioxidant capacity and modulating the NF-κB pathway in mice

Green tea polyphenols inhibit TBBPA-induced lung injury via enhancing antioxidant capacity and modulating the NF-κB pathway in mice

Prevalence of environmental microplastics in Taiwan and its impact on the seafood safety: An integrative review

The Effects of Microplastics on Musculoskeletal Disorder; A Narrative Review

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