2003
DOI: 10.1034/j.1600-051x.2003.00013.x
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Microsurgical access flap and enamel matrix derivative for the treatment of periodontal intrabony defects: a controlled clinical study

Abstract: Both treatment modalities using the microsurgical flap procedure resulted in a high percentage of primary flap closure and maximum tissue preservation. In terms of PPD reduction and CAL gain, the combination with EMD application appeared to be superior to the microsurgical access flap alone.

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Cited by 193 publications
(243 citation statements)
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“…The procedure resulted in significant gain in CAL and minimal gingival recession. Wachtel et al conducted a study on 11 patients to assess the clinical effect of EMD treatment as an adjunct to the microsurgical access flap (Wachtel H et al, 2003). Both test and control treatment resulted in a statistically significant mean CAL gain of 2.8 and 2mm at 6 months, and 3.6 and 1.7mm at 12 months, respectively.…”
Section: Discussionmentioning
confidence: 99%
“…The procedure resulted in significant gain in CAL and minimal gingival recession. Wachtel et al conducted a study on 11 patients to assess the clinical effect of EMD treatment as an adjunct to the microsurgical access flap (Wachtel H et al, 2003). Both test and control treatment resulted in a statistically significant mean CAL gain of 2.8 and 2mm at 6 months, and 3.6 and 1.7mm at 12 months, respectively.…”
Section: Discussionmentioning
confidence: 99%
“…Wachel et al 12 evaluated periodontal regeneration in 11 patients with bilateral infra bony defects. The patients were divided into 2groups: one subjected to Endogain® and microsurgery, and a control group subjected only to microsurgery.…”
Section: Discussionmentioning
confidence: 99%
“…Of the 19 studies included, nine had a split-mouth design -six with a follow-up period of 12 months (14,16,23,27,28,34) and three with duration of over 24 months (15,35,36) -and ten had a parallel design -five with a follow-up period of 12 months (10,17,(37)(38)(39) and five with a follow-up period of over 24 months (24,25,29,40,41). Regarding the evaluated outcomes, PD and CAL were evaluated in all the studies, gingival recession (GR) was additionally evaluated in eight studies (15,16,24,25,29,36,39,41) and bone filling in twelve studies (10,(14)(15)(16)(23)(24)(25)27,29,36,39,41).…”
Section: Study Characteristicsmentioning
confidence: 99%
“…One of the indications for the use of EMDPs is for the management of infrabony periodontal defects (IPD). The use of EMDP in such defects has been histologically evaluated in animals (19,20) and in humans (8,15,21,22) with promising results regarding periodontal regeneration, and their clinical results have been shown to be significantly better than those of their comparative controls (14,15,(23)(24)(25)(26)(27)(28)(29).…”
Section: Introductionmentioning
confidence: 99%