Microvascular Tissue Oxygenation and Oxidative Metabolism Changes in the Pedicled Latissimus Dorsi Muscle During Graded Hypoxia: Correlation Between Near Infrared and 31P Nuclear Magnetic Resonance Spectroscopy

Troitzsch, D; Moosdorf, Rainer; Vogt, Sebastian

doi:10.1016/j.jss.2011.04.064

Cited by 4 publications

(4 citation statements)

References 30 publications

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“…Values of StO 2 < 45% to 50% are associated with increased anaerobic metabolism and lactate production, and reductions in intracellular high‐energy phosphates correlate with reductions in StO 2 as measured by NIRS .…”

Section: Continuous Cardiac Output Monitoringmentioning

confidence: 97%

New technologies in pediatric anesthesia

Holtby

Skowno

Kor

et al. 2012

Pediatric Anesthesia

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This article reviews potential pediatric applications of 3 new technologies. (1) Pulse oximetry-based hemoglobin determination: Hemoglobin determination using spectrophotometric methods recently has been introduced in adults with varied success. This non-invasive and continuous technology may avoid venipuncture and unnecessary transfusion in children undergoing surgery with major blood loss, premature infants undergoing unexpected and complicated emergency surgery, and children with chronic illness. (2) Continuous cardiac output monitoring: In adults, advanced hemodynamic monitoring such as continuous cardiac output monitoring has been associated with better surgical outcomes. Although it remains unknown whether similar results are applicable to children, current technology enables the monitoring of cardiac output non-invasively and continuously in pediatric patients. It may be important to integrate the data about cardiac output with other information to facilitate therapeutic interventions. (3) Anesthesia information management systems: Although perioperative electronic anesthesia information management systems are gaining popularity in operating rooms, their potential functions may not be fully appreciated. With advances in information technology, anesthesia information management systems may facilitate bedside clinical decisions, administrative needs, and research in the perioperative setting.

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Section: Continuous Cardiac Output Monitoringmentioning

confidence: 97%

New technologies in pediatric anesthesia

Holtby

Skowno

Kor

et al. 2012

Pediatric Anesthesia

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“…3 Near-infrared spectroscopy (NIRS), which uses light absorption through the skin, has been proposed as a potential mechanism to continuously measure changes in muscle oxygen saturation after trauma as diagnosis of lower extremity CS. 4,5 However, definite, objective tissue oxygenation thresholds for CS still have not been determined.…”

Section: Introductionmentioning

confidence: 99%

Diagnosis of Compartment Syndrome Based on Tissue Oxygenation

Kim¹,

Liu²

2014

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“…In cerebral tissue, absolute oxyhaemoglobin saturation values below 50% are indicative of very poor perfusion, and below 40% with the onset of anaerobic metabolism (Kurth et al 2002). In rabbit muscle, StO 2 reduction below 50% is associated with the start of ATP depletion, as detected by 31 P-NMR spectroscopy (Troitzsch et al 2012). A recently developed modality, diffuse correlation spectroscopy (DCS), measures deep tissue blood flow directly, using narrowband continuous wave laser light with long coherence, but is still investigational (Mesquita et al 2011).…”

Section: Introductionmentioning

confidence: 99%

Near-infrared spectroscopy for detection of vascular compromise in paediatric supracondylar fractures

et al. 2014

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Children suffering supracondylar fractures of the humerus are at risk of vascular compromise, which is currently assessed clinically, although other modalities such as angiography, pulse oximetry, Doppler ultrasound and magnetic resonance angiography have been used. We sought to ascertain whether tissue haemoglobin oxygenation (StO2) measurement could distinguish between patients with and without clinical vascular compromise following supracondylar fractures of the humerus. We prospectively observed StO2 using near-infrared spectroscopy in 29 paediatric patients with supracondylar fractures requiring operative manipulation. The injured and uninjured volar forearm compartments were monitored immediately before and after fracture reduction. The relationship between StO2 in the injured and uninjured limb, and the presence of pre-operative vascular compromise was assessed. Seven out of 29 children presented with vascular compromise. Patients with clinical vascular compromise had significantly lower pre-reduction StO2 (63.5% ± 15%, mean ± standard deviation), compared to those without compromise (80.9% ± 10%). StO2 normalized following surgery in all children with vascular compromise. These improvements in muscle StO2 were associated, in all patients, with the clinical return of pulses and resolution of neurological symptoms if present. StO2 monitoring can identify patients with clinical vascular compromise, can identify the return of adequate perfusion following operative correction of supracondylar fractures, and may be a useful adjunct to clinical assessment.

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Microvascular Tissue Oxygenation and Oxidative Metabolism Changes in the Pedicled Latissimus Dorsi Muscle During Graded Hypoxia: Correlation Between Near Infrared and 31P Nuclear Magnetic Resonance Spectroscopy

Cited by 4 publications

References 30 publications

New technologies in pediatric anesthesia

New technologies in pediatric anesthesia

Diagnosis of Compartment Syndrome Based on Tissue Oxygenation

Near-infrared spectroscopy for detection of vascular compromise in paediatric supracondylar fractures

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