Microwave Ablation for the Treatment of Hepatic Adenomas

Smolock, Amanda R.; Cristescu, M.; Potretzke, Theodora A.; Ziemlewicz, Timothy J.; Lubner, Meghan G.; Hinshaw, J. Louis; Brace, Christopher L.; Lee, Fred T.

doi:10.1016/j.jvir.2015.09.021

Cited by 29 publications

(22 citation statements)

References 18 publications

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“…Two patients presented with liver cirrhosis related to virus B infection or alcoholic abuse, while no patient had predisposing factors for HCA, such as history of oral contraceptives or steroid therapy. No signs of cirrhosis were reported in other studies [10][11][12][13]. The patients treated in the other series were mostly asymptomatic except for a declared history of HCA-related hemorrhage present only in 11% and 22% of cases [10,12].…”

Section: Patient Characteristicsmentioning

confidence: 60%

“…The use of oral contraceptives was the main predisposing factor [10][11][12]. The decision to pursue percutaneous ablation therapy was based on a multidisciplinary discussion [12,13], or established considering multiple factors. Ablation was performed in patients not amenable to surgery in view of comorbidities, location or number of the lesions, or in cases otherwise requiring large liver resections [10,13], owing to an expected lower rate of procedural complications compared with surgery [13].…”

Section: Patient Characteristicsmentioning

confidence: 99%

“…The decision to pursue percutaneous ablation therapy was based on a multidisciplinary discussion [12,13], or established considering multiple factors. Ablation was performed in patients not amenable to surgery in view of comorbidities, location or number of the lesions, or in cases otherwise requiring large liver resections [10,13], owing to an expected lower rate of procedural complications compared with surgery [13]. Van Vledder et al treated 18 women with HCAs and, in this population, the desire to become pregnant was a relevant motivation to consider the intervention [10].…”

Section: Patient Characteristicsmentioning

confidence: 99%

“…In most patients the diagnosis was confirmed by biopsy after imaging evaluation and prior to ablation, except for one patient [13] in which clinical and imaging findings were highly suggestive for HCA and biopsy was not obtained, and a series [10] in which the diagnosis was based on radiology data alone, including contrast-enhanced magnetic resonance (MR) and multiphasic computed tomography (CT) imaging.…”

Section: Patient Characteristicsmentioning

confidence: 99%

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Current concepts in ablative procedures for primary benign liver lesions: a step forward to minimize the invasiveness of treatment when deemed necessary

et al. 2020

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With increased use of medical imaging, the incidental detection of benign solid liver tumors has become more frequent. Facing with benign disease, the indications for surgery are still object of discussion in light of the stable natural course of most lesions and obvious drawbacks of any surgical intervention; therefore, in most situations, a conservative approach is recommended, and surgery is mainly reserved for those cases with persistent or worsening symptoms, or who are at risk for complications as malignant transformation. The advent of ablative techniques has widened the range of treatment options available to these patients, presenting as a valid alternative to resection in terms of safety and efficacy in selected cases, particularly in patients who are considered poor surgical candidates and with smaller lesions. This review outlines the role of percutaneous ablative methods for benign solid liver tumors that are encountered in adults, providing a per histology analysis of the existing evidence. The up-to-date strategies for management of the most common benign solid tumors are recapitulated.

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Section: Patient Characteristicsmentioning

confidence: 60%

Section: Patient Characteristicsmentioning

confidence: 99%

Section: Patient Characteristicsmentioning

confidence: 99%

Section: Patient Characteristicsmentioning

confidence: 99%

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Current concepts in ablative procedures for primary benign liver lesions: a step forward to minimize the invasiveness of treatment when deemed necessary

et al. 2020

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“…Up to now, microwaves find a biomedical application in a microwave therapy [117,118] and, therefore, can be employed to trigger a release from the microcapsules in the human body. Up to now, microwaves find a biomedical application in a microwave therapy [117,118] and, therefore, can be employed to trigger a release from the microcapsules in the human body.…”

Section: Microwave Triggeringmentioning

confidence: 99%

Inorganic/Organic Multilayer Capsule Composition for Improved Functionality and External Triggering

Timin

Gao

Voronin

et al. 2016

Adv Materials Inter

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Polyelectrolyte (PE) and nanocomposite (NC) microcapsules fabricated by layer‐by‐layer technique have been of great interest in the past decade as novel entities for cargo encapsulation and delivery as well as for diagnostic purposes. The unique physicochemical properties of polymers and inorganic nanoparticles used in layer‐by‐layer synthesis of PE and NC microcapsules make them promising in various fields, such as storage, catalysis, cells imaging, controlled drug release, and targeted drug delivery. However, the requirement of the cargo encapsulation is that the cargo should have a relatively large molecular weight in order to avoid the leakage from the capsules. In this review, recent progress in the design and functionalization of PE and NC microcapsules using sol–gel method for storage of small cargos have been presented. Moreover, various remote exposures on the permeability of organic/inorganic composite microcapsule shells such as ultrasound, magnetic field gradient, laser, and microwave radiation have been observed. Finally, the description and discussion of the new trends and perspectives for improved functionality of PE microcapsules are the major topic of this progress report.

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