Microwave-assisted extraction, partial purification and biological activity in vitro of polysaccharides from bladder-wrack (Fucus vesiculosus) by using deep eutectic solvents

Shang, Xingfu; Chu, Depeng; Ji-xu, Zhang; Zheng, Yanfen; Li, Yiqiang

doi:10.1016/j.seppur.2020.118169

Cited by 90 publications

(54 citation statements)

References 39 publications

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“…DES can be served as extracting solvent for multiple bioactive components, such as flavonoids, phenolic acids, and alkaloids [12]. Notably, DES has also been utilized to extract various polysaccharides from plants, which has been proven to exhibit higher extraction yield than that of traditional extraction solvent [14][15][16]. Therefore, all data suggests that DES possesses good potential for efficient extraction of polysaccharides from edible and medicinal plants.…”

Section: Introductionmentioning

confidence: 99%

Deep Eutectic Solvent-Assisted Extraction, Partially Structural Characterization, and Bioactivities of Acidic Polysaccharides from Lotus Leaves

Feng

Huang

et al. 2021

Foods

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Lotus leaves are often discarded as byproducts in the lotus industry. Polysaccharides are regarded as one of the essentially bioactive components in lotus leaves. Therefore, in order to promote the application of lotus leaves in the functional food industry, the deep eutectic solvent (DES) assisted extraction of polysaccharides from lotus leaves (LLPs) was optimized, and structural and biological properties of LLPs extracted by DES and hot water were further investigated. At the optimal extraction conditions (water content of 61.0% in DES, extraction temperature of 92 °C, liquid-solid ratio of 31.0 mL/g and extraction time of 126 min), the maximum extraction yield (5.38%) was obtained. Furthermore, LLP-D extracted by DES and LLP-W extracted by hot water possessed the same sugar residues, such as 1,4-α-D-GalAp, 1,4-α-D-GalAMep, 1,3,6-β-D-Galp, 1,4-β-D-Galp, 1,5-α-L-Araf, and 1,2-α-L-Rhap, suggesting the presence of homogalacturonan (HG), rhamnogalacturonan I and arabinogalactan in both LLP-W and LLP-D. Notably, LLP-D was much richer in HG fraction than that of LLP-W, suggesting that the DES could assist to specifically extract HG from lotus leaves. Additionally, the lower molecular weight and higher content of uronic acids were observed in LLP-D, which might contribute to its much stronger in vitro antioxidant, hypoglycemic, and immunomodulatory effects. These findings suggest that the optimized DES assisted extraction method can be a potential approach for specific extraction of acidic polysaccharides with good bioactivities from lotus leaves for applications in the functional food industry.

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Section: Introductionmentioning

confidence: 99%

Deep Eutectic Solvent-Assisted Extraction, Partially Structural Characterization, and Bioactivities of Acidic Polysaccharides from Lotus Leaves

Feng

Huang

et al. 2021

Foods

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“…Recently, a biphasic system based on deep eutectic solvents was proposed for the simultaneous extraction of high polarity chlorogenic acid, quercetin, anthocyanidins, and a low polarity compound artemisinin from Artemisia [20]. Several papers report the application of NADES for the recovery of bioactive compounds from seaweeds [19,[21][22][23][24].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Natural Deep Eutectic Solvents for Extraction of Hydrophilic and Lipophilic Compounds from Fucus vesiculosus

et al. 2021

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The impact of the composition of natural deep eutectic solvents (NADES) and extraction conditions on the simultaneous extraction of hydrophilic ascorbic acid (AA), phlorotannins (TPhC), and lipophilic fucoxanthin (FX) from Fucus vesiculosus was investigated for the first time. In biological tests, the NADES extracts showed the promising ability to scavenge DPPH radicals. A positive correlation was observed between DPPH scavenging activity and AA, TPhC, and FX contents. We calculate the synergistic effect of antioxidants extracted by NADES from F. vesiculosus based on the mixture effect (ME). The addition of 30% water to the NADES and the prolongation of sonication time from 20 min up to 60 min were favorable for the ME. The ME for extracts with the NADES was increased by two folds (ME > 2). In contrast, conventional extraction by maceration with steering at 60 °C does not lead to the synergistic effect (ME = 1). It is notable that the NADES provides high stability and preserves the antioxidant activity of the extracts from F. vesiculosus during storage.

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“…Additionally, microwave-assisted extraction using deep eutectic solvent was employed for the extraction of polysaccharides from Fucus vesiculosus. A maximum of 116.33 mg/g of polysaccharide was procured in 35 min at 168 ℃ with excellent antioxidant and anticancer activities in vitro [ 90 ]. Figure 4 shows the schematic diagram of the microwave-assisted extraction of polysaccharides from seaweeds.…”

Section: Advanced Extraction Methodologies For Algal Polysaccharidesmentioning

confidence: 99%

Perspective on the Therapeutic Applications of Algal Polysaccharides

et al. 2021

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Algae are an enormous source of polysaccharides and have gained much interest in human flourishing as organic drugs. Algal polysaccharides have aroused interest in the health sector owing to the various bioactivities namely anticancer, antiviral, immunoregulation, antidiabetic and antioxidant effects. The research community has comprehensively described the importance of algal polysaccharides regarding their extraction, purification, and potential use in various sectors. However, regardless of all the intriguing properties and potency in the health sector, these algal polysaccharides deserve detailed investigation. Hence, the present review emphasizes extensively on the previous and latest developments in the extraction, purification, structural properties and therapeutic bioactivities of algal polysaccharides to upgrade the knowledge for further advancement in this area of research. Moreover, the review also addresses the challenges, prospective research gaps and future perspective. We believe this review can provide a boost to upgrade the traditional methods of algal polysaccharide production for the development of efficacious drugs that will promote human welfare.

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Microwave-assisted extraction, partial purification and biological activity in vitro of polysaccharides from bladder-wrack (Fucus vesiculosus) by using deep eutectic solvents

Cited by 90 publications

References 39 publications

Deep Eutectic Solvent-Assisted Extraction, Partially Structural Characterization, and Bioactivities of Acidic Polysaccharides from Lotus Leaves

Deep Eutectic Solvent-Assisted Extraction, Partially Structural Characterization, and Bioactivities of Acidic Polysaccharides from Lotus Leaves

Efficacy of Natural Deep Eutectic Solvents for Extraction of Hydrophilic and Lipophilic Compounds from Fucus vesiculosus

Perspective on the Therapeutic Applications of Algal Polysaccharides

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