Microwave-Assisted Synthesis, Optical and Theoretical Characterization of Novel 2-(imidazo[1,5-a]pyridine-1-yl)pyridinium Salts

Cavinato, Luca M.; Volpi, Giorgio; Fresta, Elisa; Garino, Claudio; Fin, Andréa; Barolo, Claudia

doi:10.3390/chemistry3030050

Cited by 10 publications

(6 citation statements)

References 52 publications

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“…Despite this, the development of new Cu(I) complexes for blue LEC design remains largely unexplored. In this context, imidazopyridinic derivatives emerge as a promising alternative to complexes based on the more widely recognized bipyridine and phenanthroline [ 39 , 40 , 53 , 54 , 55 , 57 , 147 , 148 ].…”

Section: Studies and Applications Of Imidazopyridine Derivativesmentioning

confidence: 99%

Imidazopyridine Family: Versatile and Promising Heterocyclic Skeletons for Different Applications

Volpi,

Laurenti,

Rabezzana

2024

Molecules

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In recent years, there has been increasing attention focused on various products belonging to the imidazopyridine family; this class of heterocyclic compounds shows unique chemical structure, versatile optical properties, and diverse biological attributes. The broad family of imidazopyridines encompasses different heterocycles, each with its own specific properties and distinct characteristics, making all of them promising for various application fields. In general, this useful category of aromatic heterocycles holds significant promise across various research domains, spanning from material science to pharmaceuticals. The various cores belonging to the imidazopyridine family exhibit unique properties, such as serving as emitters in imaging, ligands for transition metals, showing reversible electrochemical properties, and demonstrating biological activity. Recently, numerous noteworthy advancements have emerged in different technological fields, including optoelectronic devices, sensors, energy conversion, medical applications, and shining emitters for imaging and microscopy. This review intends to provide a state-of-the-art overview of this framework from 1955 to the present day, unveiling different aspects of various applications. This extensive literature survey may guide chemists and researchers in the quest for novel imidazopyridine compounds with enhanced properties and efficiency in different uses.

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Section: Studies and Applications Of Imidazopyridine Derivativesmentioning

confidence: 99%

Imidazopyridine Family: Versatile and Promising Heterocyclic Skeletons for Different Applications

Volpi,

Laurenti,

Rabezzana

2024

Molecules

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“…Their optical properties were used to assess the quantization that affected the optical characteristics of the polymeric matrix in the solution. 67 Mishra et al synthesized 6H-chromeno[4′,3′:4,5]imidazo[1,2-a]pyridine derivatives 137 (Scheme 31) under microwave irradiation in an effective one-pot Michael addition-cyclization reaction. This procedure has several notable advantages, including rapid reaction times, ease of operation, and tolerance to a broad range of functional groups.…”

Section: Review Synopenmentioning

confidence: 99%

“…Their optical properties were used to assess the quantization that affected the optical characteristics of the polymeric matrix in the solution. 67…”

Section: Imidazo Pyridine Hybridsmentioning

confidence: 99%

Microwave-Assisted Synthesis of Heterocyclic Scaffolds

Agarwal,

Kumar,

Maurya

2024

SynOpen

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In recent years, there has been a notable surge in the utilization of microwave energy, leading to the emergence of innovative and groundbreaking methods across various branches of chemistry, including organic synthesis, materials science, heterocyclic chemistry, and medicinal chemistry. This comprehensive literature review delves into the microwave-assisted organic synthesis of specific heterocycles, illuminating its effectiveness in producing diverse molecules with heightened efficiency and selectivity. The review highlights the significant role of microwave irradiation as a potent method for constructing a wide range of compounds. Particular emphasis is placed on the impact of the technique on synthesizing various hybrids such as 1,2,3-triazole hybrids, coumarin hybrids, imidazopyridine hybrids, phenanthridines hybrids, carbene hybrids, and oxazole hybrids. This article is valuable as it offers insights into current synthetic procedures and trends in developing innovative medications utilizing heterocyclic compounds.1 Introduction2 Synthesis of 1,2,3-Triazole Hybrids3 Coumarin Hybrids4 Imidazo Pyridine Hybrids5 Phenanthridine Hybrids6 Carbene Hybrids7 Oxazole Hybrids8 Conclusion

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“…One-pot microwave-assisted condensation of substituted methanones 82 with benzaldehyde, isophthalaldehyde, or terephthalaldehyde 83 or 84 in the presence of NH 4 OAc produced 85a-c . The method yielded water as a byproduct and occurred in the absence of any highly sensitive Lewis acids [ 56 ]. The imidazo[1,5- a ]pyridine scaffolds containing compounds are found to have good antibacterial activities [ 57 ].…”

Section: Synthetic Approach For Biologically Significant Pyridine Com...mentioning

confidence: 99%

Recent Advances in Pyridine Scaffold: Focus on Chemistry, Synthesis, and Antibacterial Activities

Islam

Nath

et al. 2023

BioMed Research International

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Multidrug-resistant (MDR) pathogens have created a fatal problem for human health and antimicrobial treatment. Among the currently available antibiotics, many are inactive against MDR pathogens. In this context, heterocyclic compounds/drugs play a vital role. Thus, it is very much essential to explore new research to combat the issue. Of the available nitrogen-bearing heterocyclic compounds/drugs, pyridine derivatives are of special interest due to their solubility. Encouragingly, some of the newly synthesized pyridine compounds/drugs are found to inhibit multidrug-resistant S. aureus (MRSA). Pyridine scaffold bearing poor basicity generally improves water solubility in pharmaceutically potential molecules and has led to the discovery of numerous broad-spectrum therapeutic agents. Keeping these in mind, we have reviewed the chemistry, recent synthetic techniques, and bacterial preventative activity of pyridine derivatives since 2015. This will facilitate the development of pyridine-based novel antibiotic/drug design in the near future as a versatile scaffold with limited side effects for the next-generation therapeutics.

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Microwave-Assisted Synthesis, Optical and Theoretical Characterization of Novel 2-(imidazo[1,5-a]pyridine-1-yl)pyridinium Salts

Cited by 10 publications

References 52 publications

Imidazopyridine Family: Versatile and Promising Heterocyclic Skeletons for Different Applications

Imidazopyridine Family: Versatile and Promising Heterocyclic Skeletons for Different Applications

Microwave-Assisted Synthesis of Heterocyclic Scaffolds

Recent Advances in Pyridine Scaffold: Focus on Chemistry, Synthesis, and Antibacterial Activities

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