Mid and Near Infrared Spectroscopy

Reich, Gabriele

doi:10.1007/978-1-4939-4029-5_3

Cited by 7 publications

(2 citation statements)

References 337 publications

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“…The 4000 − 400 cm −1 MIR area is the most commonly used infrared region for biological applications, which includes the so-called fingerprint regions representative for lipids, proteins, amide I/II, carbohydrates, and nucleic acids (Figure 1). More insights on these two powerful analytical tools can be found in Reich’s book chapter [2] that focuses on modern pharmaceutical MIR and NIR applications starting from basic principles of both techniques, sampling of solid drug molecules and excipients, and up to data processing. FIR spectroscopy (400 − 20 cm −1 ) provides information on the highly ordered structures such as fibrillar formation and protein dynamics [3], since it is more sensitive to the vibrations from the peptide skeletons and hydrogen bonds than MIR [4].…”

Section: Introductionmentioning

confidence: 99%

Vibrational Spectroscopy Fingerprinting in Medicine: from Molecular to Clinical Practice

et al. 2019

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In the last two decades, Fourier Transform Infrared (FTIR) and Raman spectroscopies turn out to be valuable tools, capable of providing fingerprint-type information on the composition and structural conformation of specific molecular species. Vibrational spectroscopy’s multiple features, namely highly sensitive to changes at the molecular level, noninvasive, nondestructive, reagent-free, and waste-free analysis, illustrate the potential in biomedical field. In light of this, the current work features recent data and major trends in spectroscopic analyses going from in vivo measurements up to ex vivo extracted and processed materials. The ability to offer insights into the structural variations underpinning pathogenesis of diseases could provide a platform for disease diagnosis and therapy effectiveness evaluation as a future standard clinical tool.

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Section: Introductionmentioning

confidence: 99%

Vibrational Spectroscopy Fingerprinting in Medicine: from Molecular to Clinical Practice

et al. 2019

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“…Near infrared and mid infrared are two adjacent spectral regions, with NIR being immediately after the visible, moving to the longer wavelength region [2] (Figure 1). When a sample matrix is presented to the infrared light, molecular vibrations are measured through the absorbances at each wavelength and from this absorbances associated to specific chemical bonds are made.…”

Section: Background On Infrared (Near and Mid)mentioning

confidence: 99%

The Brewing Industry and the Opportunities for Real-Time Quality Analysis Using Infrared Spectroscopy

Fox

2020

Applied Sciences

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Brewing is an ancient process which started in the middle east over 10,000 years ago. The style of beer varies across the globe but modern brewing is very much the same regardless of the style. While there are thousands of compounds in beer, current methods of analysis rely mostly on the content of only several important processing parameters such as gravity, bitterness, or alcohol. Near infrared and mid infrared spectroscopy offer opportunities to predict dozens to hundreds of compounds simultaneously at different stages of the brewing process. Importantly, this is an opportunity to move deeper into quality through measuring wort and beer composition, rather than just content. This includes measuring individual sugars and amino acids prior to fermentation, rather than total °Plato or free amino acids content. Portable devices and in-line probes, coupled with more complex algorithms can provide real time measurements, allowing brewers more control of the process, resulting in more consistent quality, reduced production costs and greater confidence for the future.

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