“…As far as we know, diastolic opening of the AV in AR has been reported in 10 articles ( Table 1 ). 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 It was first reported by Page and Layton 1 in Marfan syndrome. Other conditions showing late diastolic opening of the AV were perforation of the leaflet secondary to infectious endocarditis, prolapse of the AV, and aortic dissection.…”