“…Limited (Fienberg, 1953;Carrington and Liebow, 1966) 2. Systemic (Wegener, 1936(Wegener, , 1939 The surgeon and the pathologist faced with a patient suffering from prolonged nasal or midfacial ulceration have a dif cult path to tread, as pointed out in several papers (Friedmann, 1955(Friedmann, , 1964(Friedmann, , 1971(Friedmann, , 1976. A long list of more or less wellde ned granulomas and/or neoplasms has to be considered, recognized or eliminated in the differential diagnosis of the 'midfacial granuloma syndrome' Osborn, 1976, 1981).…”