Midterm results after complete surgical correction of transposition of the great arteries

Parezanović, Vojislav; Mrdjen, Mirko; Illić, Slobodan; Vuličević, Irena; Djukic, Milan; Jovanovic, Ida; Stefanovic, Igor; Illisić, Tamara; Kalanj, Jasna; Mimic, Branko; Milovanović, Vladimir

doi:10.2298/sarh1406306p

Cited by 5 publications

(7 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, simple TGA was found to be slightly more common than the complex forms, a finding which agrees with postnatal series [6,28] but that contrasts with previous prenatal studies reporting that the latter are more common [22]. These discrepancies may be attributed to the degree of distortion of cardiac anatomy that both types of TGA have, and hence, the ease of prenatal detection.…”

Section: Discussionsupporting

confidence: 75%

See 1 more Smart Citation

Transposition of the Great Arteries in Fetal Life: Accuracy of Diagnosis and Short-Term Outcome

Domínguez-Manzano

Mendoza²,

Herraı̀z³

et al. 2016

Fetal Diagn Ther

View full text Add to dashboard Cite

Objective: To review our series of prenatally diagnosed transposition of the great arteries (TGA) to analyze the accuracy of fetal echocardiography for achieving a precise diagnosis of the TGA type (simple vs. complex) and to examine the short-term outcome. Methods: A total of 94 cases of simple and complex TGA types (ventriculoarterial discordance with atrioventricular concordance) prenatally evaluated in our referral center between 1998 and 2014 were included. Fetuses with additional congenital anomalies and those with incomplete follow-up were excluded. Prenatal diagnostic accuracy and short-term survival were analyzed for the different types of TGA. Results: The TGA type was correctly ascertained prenatally in 93.3%. Most fetuses were diagnosed with simple TGA (62.7%). There were 6 discrepancies: 5 fetuses with simple TGA had postnatally TGA + ventricular septal defect (VSD; n = 3) or TGA + VSD + coarctation of the aorta (n = 2), and 1 fetus with TGA + VSD postnatally showed severe left ventricular outflow tract obstruction. The mortality rate was 6.6%; it was higher in complex versus simple forms (12.8 vs. 1.9%, p = 0.038), and in cases with intramural coronary artery versus those without (60 vs. 3.5%, p < 0.001). We found no relationship between the arrangement of the great arteries and coronary arterial abnormalities. Conclusions: Simple TGA has a better outcome than the complex forms. A discrepancy rate of 7% with potential influence on the prognosis of survival between the prenatal diagnosis of the TGA type and the definitive diagnosis was found.

show abstract

Section: Discussionsupporting

confidence: 75%

“…Although TGA situates among the major CHD with the best outcome results [4], the survival rate reported differs widely between series, from 75-80% to 98-99%, depending on factors such as the type of TGA or the presence of coronary anomalies [5,6,7,8,9,10]. …”

Section: Introductionmentioning

confidence: 99%

Transposition of the Great Arteries in Fetal Life: Accuracy of Diagnosis and Short-Term Outcome

Domínguez-Manzano

Mendoza²,

Herraı̀z³

et al. 2016

Fetal Diagn Ther

View full text Add to dashboard Cite

show abstract

“…The majority (79.5%) of patients underwent neonatal arterial switch. At the time of operation, the median age was 13 days (IQR, [9][10][11][12][13][14][15][16][17][18][19][20][21][22], and the median weight was 3.5 kg (IQR, 3.2-3.9). The most frequent prior procedure was a Rashkind balloon atrial septostomy performed in 62 (48.8%) patients.…”

Section: Resultsmentioning

confidence: 99%

“…Shim et al reported an astonishing mortality rate of 2.2% among a cohort of 139 patients who underwent an arterial switch operation between 1995 and 2014 in South Korea [ 15 ]. However, other authors from small and medium case-load centers have reported overall surgical mortalities ranging from 4.8 to 28% [ 14 , 20 , 21 , 22 ]. Similar to the experience of large centers, surgical mortality rates tend to decrease with time [ 14 , 15 , 20 , 21 ].…”

Section: Discussionmentioning

confidence: 99%

“…However, other authors from small and medium case-load centers have reported overall surgical mortalities ranging from 4.8 to 28% [ 14 , 20 , 21 , 22 ]. Similar to the experience of large centers, surgical mortality rates tend to decrease with time [ 14 , 15 , 20 , 21 ]. Shim et al reported that two out of three patients who died during the 30 post-operative days were operated on at the beginning of the arterial switch program [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Early and Late Outcomes after Arterial Switch Operation: A 40-Year Journey in a Single Low Case Volume Center

et al. 2021

View full text Add to dashboard Cite

Background and Objectives: The results of the arterial switch operation in large congenital heart centers are excellent, and the results in small and medium centers are improving. The objective of this article is to share our experience utilizing the international knowledge transfer program to improve early and late arterial switch operation outcomes in our center. Materials and Methods: A retrospective analysis of patients who underwent the arterial switch operation in Vilnius University Santaros Clinics Cardiothoracic Surgery Center between 1977–2020 was performed. Results: A total of 127 consecutive arterial switch operations were performed in our center. Surgical mortality during the entire study period was 24.6%. Surgical mortality prior to the program, during the program, and after the program was 88.24%, 41.7%, and 5.81%, respectively (p < 0.0001). The surgical mortality of patients operated on during the last 10 years was 4%. The overall survival estimate for the 97 surviving patients was 96.9%, 94.9%, 93.8%, 93.8%, 93.8%, 93.8% at 1, 3, 5, 10, 15, and 20 years, respectively. Risk factors for early mortality included longer aortic cross-clamp time and operation prior to the knowledge transfer program. The only significant risk factor for late reintervention was concomitant aortic arch obstruction treated at the time of the arterial switch. Conclusions: The surgical treatment of transposition of the great arteries by means of an arterial switch with good results can be possible in low-to-medium volume congenital heart surgery centers. International knowledge transfer programs between high-expertise high-volume congenital heart centers and low-to-medium volume congenital heart centers may help to shorten the learning curve and improve early and late outcomes after an arterial switch. The risk factors for surgical mortality and intervention-free survival in low-volume surgical centers are similar to those in high-volume centers. Late arterial switch-related complications are similar to those among different-sized congenital heart centers.

show abstract

Impact of prenatal diagnosis of transposition of the great arteries on postnatal outcome

Domínguez-Manzano

Herraı̀z

Mendoza

et al. 2016

The Journal of Maternal-Fetal & Neonatal Medicine

View full text Add to dashboard Cite

show abstract

Midterm results after complete surgical correction of transposition of the great arteries

Abstract: Arterial switch operation has been successfully performed at our institution, with acceptable perioperative mortality and excellent late outcome.

Cited by 5 publications

References 0 publications

Transposition of the Great Arteries in Fetal Life: Accuracy of Diagnosis and Short-Term Outcome

Transposition of the Great Arteries in Fetal Life: Accuracy of Diagnosis and Short-Term Outcome

Early and Late Outcomes after Arterial Switch Operation: A 40-Year Journey in a Single Low Case Volume Center

Impact of prenatal diagnosis of transposition of the great arteries on postnatal outcome

Contact Info

Product

Resources

About