2019
DOI: 10.1159/000494625
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Milk Curd Obstruction in Human Milk-Fed Preterm Infants

Abstract: Background: Milk curd obstruction as a cause of intestinal obstruction has been known since 1959, but has nearly disappeared. However, in recent years it has experienced a revival in small premature infants. Objective: The aim of this study was to evaluate the clinical characteristics of milk curd obstruction (lactobezoar) in preterm infants. Methods: Data of preterm infants with milk curd obstruction cared for at a large tertiary neonatal intensive care unit between 2012 and 2016 were retrieved from the elect… Show more

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Cited by 14 publications
(31 citation statements)
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“…Lactobezoar is mainly composed of undigested milk and mucus protein or fatty acid calcium stone (Heinz-Erian et al, 2012;Murase et al, 2013). It occurs mainly in neonates who are either premature or small for gestational age (Longardt et al, 2019). The case numbers decreased after the 1980s, possibly due to the advancement of neonatal care and the improvement of formula manufacturing (Iwamuro et al, 2015).…”
Section: Discussionmentioning
confidence: 99%
“…Lactobezoar is mainly composed of undigested milk and mucus protein or fatty acid calcium stone (Heinz-Erian et al, 2012;Murase et al, 2013). It occurs mainly in neonates who are either premature or small for gestational age (Longardt et al, 2019). The case numbers decreased after the 1980s, possibly due to the advancement of neonatal care and the improvement of formula manufacturing (Iwamuro et al, 2015).…”
Section: Discussionmentioning
confidence: 99%
“…When we compared our experiences with published case studies of ileal milk curd, 1 this led us to conclude that gastric localisation seems to have a more benign evolution, with complete resolution after conservative management and no need for surgery.…”
Section: Figurementioning
confidence: 99%
“…The infant was discharged at 27 days of life, when she was 37 + 2 weeks of postmenstrual age.Milk curd is an undigested milk concretion, which rarely occur in infants, but is a known cause of gastrointestinal obstruction. The main risk factors are prematurity and low birth weight 1.…”
mentioning
confidence: 99%
“…The current guidelines on pediatric parenteral nutrition (PN) are based on a theoretical model and lack recommendations for extremely preterm infants 5 . In enteral nutrition, achieving adequate mineral supply is also difficult because of a low gut‐absorption rate of Ca (∼50%–60%) and a risk of milk curd obstruction 6 . Additionally, gut‐absorption rates of Ca are reduced with vitamin D deficiency.…”
Section: Introductionmentioning
confidence: 99%